New insights into the tumor suppression function of P27Kip1

被引:79
作者
Clurman, BE
Porter, P
机构
[1] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98109 USA
[2] Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98109 USA
[3] Univ Washington, Sch Med, Dept Med, Seattle, WA 98195 USA
[4] Univ Washington, Sch Med, Dept Pathol, Seattle, WA 98195 USA
关键词
D O I
10.1073/pnas.95.26.15158
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:15158 / 15160
页数:3
相关论文
共 55 条
  • [41] Singh SP, 1998, CANCER RES, V58, P1730
  • [42] Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2
    Soucek, T
    Yeung, RS
    Hengstschläger, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (26) : 15653 - 15658
  • [43] Role of the tuberous sclerosis gene-2 product in cell cycle control - Loss of the tuberous sclerosis gene-2 induces quiescent cells to enter S phase
    Soucek, T
    Pusch, O
    Wienecke, R
    DeClue, JE
    Hengstschlager, M
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (46) : 29301 - 29308
  • [44] Spirin KS, 1996, CANCER RES, V56, P2400
  • [45] Ras activity late in G(1) phase required for p27(kip1) downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
    Takuwa, N
    Takuwa, Y
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (09) : 5348 - 5358
  • [46] Tan P, 1997, CANCER RES, V57, P1259
  • [47] P27, A NOVEL INHIBITOR OF G1 CYCLIN-CDK PROTEIN-KINASE ACTIVITY, IS RELATED TO P21
    TOYOSHIMA, H
    HUNTER, T
    [J]. CELL, 1994, 78 (01) : 67 - 74
  • [48] Tsihlias J, 1998, CANCER RES, V58, P542
  • [49] Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products
    van Slegtenhorst, M
    Nellist, M
    Nagelkerken, B
    Cheadle, J
    Snell, R
    van den Ouweland, A
    Reuser, A
    Sampson, J
    Halley, D
    van der Sluijs, P
    [J]. HUMAN MOLECULAR GENETICS, 1998, 7 (06) : 1053 - 1057
  • [50] Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
    vanSlegtenhorst, M
    deHoogt, R
    Hermans, C
    Nellist, M
    Janssen, B
    Verhoef, S
    Lindhout, D
    vandenOuweland, A
    Halley, D
    Young, J
    Burley, M
    Jeremiah, S
    Woodward, K
    Nahmias, J
    Fox, M
    Ekong, R
    Osborne, J
    Wolfe, J
    Povey, S
    Snell, RG
    Cheadle, JP
    Jones, AC
    Tachataki, M
    Ravine, D
    Sampson, JR
    Reeve, MP
    Richardson, P
    Wilmer, F
    Munro, C
    Hawkins, TL
    Sepp, T
    Ali, JBM
    Ward, S
    Green, AJ
    Yates, JRW
    Kwiatkowska, J
    Henske, EP
    Short, MP
    Haines, JH
    Jozwiak, S
    Kwiatkowski, DJ
    [J]. SCIENCE, 1997, 277 (5327) : 805 - 808