MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013-2014

被引：76

作者：

Khalafalla, Abdelmalik I. ^{[1
]}

Lu, Xiaoyan ^{[2
]}

Al-Mubarak, Abdullah I. A. ^{[1
]}

Dalab, Abdul Hafeed S. ^{[1
]}

Al-Busadah, Khalid A. S. ^{[1
]}

Erdman, Dean D. ^{[2
]}

机构：

[1] King Faisal Univ, Al Hasa, Saudi Arabia

[2] Ctr Dis Control & Prevent, Atlanta, GA 30329 USA

来源：

EMERGING INFECTIOUS DISEASES | 2015年 / 21卷 / 07期

关键词：

MIDDLE-EAST; SYNDROME CORONAVIRUS; CLINICAL-FEATURES; PCR ASSAY; ANTIBODIES; TRANSMISSION; INFECTIONS; LIVESTOCK; CHILDREN;

D O I：

10.3201/eid2107.150070

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To assess the temporal dynamics of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in dromedary camels, specimens were collected at 1-2 month intervals from 2 independent groups of animals during April 2013 May 2014 in Al-Ahsa Province, Saudi Arabia, and tested for MERS-CoV RNA by reverse transcription PCR. Of 96 live camels, 28 (29.2%) nasal swab samples were positive; of 91 camel carcasses, 56 (61.5%) lung tissue samples were positive. Positive samples were more commonly found among young animals (<4 years of age) than adults (>= 4 years of age). The proportions of positive samples varied by month for both groups; detection peaked during November 2013 and January 2014 and declined in March and May 2014. These findings further our understanding of MERS-CoV infection in dromedary camels and may help inform intervention strategies to reduce zoonotic infections.

引用

页码：1153 / 1158

页数：6

共 36 条

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