Detection of amines and unprotected amino acids in aqueous conditions by formation of highly fluorescent iminium ions

被引：177

作者：

Feuster, EK ^{[1
]}

Glass, TE ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 52期

关键词：

D O I：

10.1021/ja036434m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Properly substituted coumarin aldehydes can be used to detect amines and amino acids under neutral, high ionic strength conditions by the formation of highly fluorescent iminium ions. The fluorescence of one sensor increases by 26-fold upon the addition of glycine. This strong florescent response is attributed to hydrogen bonding of the chromophore carbonyl by the acidic iminium proton. Copyright © 2003 American Chemical Society.

引用

页码：16174 / 16175

页数：2

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