Conjugated linoleic acid: Implications for human health

被引:212
作者
Whigham, LD
Cook, ME
Atkinson, RL [1 ]
机构
[1] Univ Wisconsin, Dept Med, Madison, WI 53706 USA
[2] Univ Wisconsin, Dept Nutrit Sci, Madison, WI USA
[3] Univ Wisconsin, Dept Anim Sci, Madison, WI USA
关键词
cancer; body composition; obesity; immune function; heart disease;
D O I
10.1006/phrs.2000.0735
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Conjugated linoleic acid (CLA) is being sold as a panacea that has the capability of reducing or eliminating cancer, preventing heart disease, improving immune function, and altering body composition to treat obesity or build lean body mass. Unfortunately, there has been very little published human research on CLA. This review will examine the literature on CLA and discuss the animal research on which the above claims are made. The limited human studies will be presented with an evaluation of the potential uses of CLA for human health and disease. (C) 2000 Academic Press.
引用
收藏
页码:503 / 510
页数:8
相关论文
共 77 条
[1]  
Atkinson RL, 1999, ADVANCES IN CONJUGATED LINOLEIC ACID RESEARCH, VOL 1, P348
[2]  
Azain MJ, 2000, J NUTR, V130, P1548
[3]   An increase in vitamin A status by the feeding of conjugated linoleic acid [J].
Banni, S ;
Angioni, E ;
Casu, V ;
Melis, MP ;
Scrugli, S ;
Carta, G ;
Corongiu, FP ;
Ip, C .
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1999, 33 (01) :53-57
[4]   Decrease in linoleic acid metabolites as a potential mechanism in cancer risk reduction by conjugated linoleic acid [J].
Banni, S ;
Angioni, E ;
Casu, V ;
Melis, MP ;
Carta, G ;
Corongiu, FP ;
Thompson, H ;
Ip, C .
CARCINOGENESIS, 1999, 20 (06) :1019-1024
[5]   Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion [J].
Belury, MA ;
Nickel, KP ;
Bird, CE ;
Wu, YM .
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1996, 26 (02) :149-157
[6]   Dietary conjugated linoleic acid induces peroxisome-specific enzyme accumulation and ornithine decarboxylase activity in mouse liver [J].
Belury, MA ;
MoyaCamarena, SY ;
Liu, KL ;
Heuvel, JPV .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 1997, 8 (10) :579-584
[7]  
BOUGNOUX P, 1999, INFORM, V10, pS43
[8]  
Brodie AE, 1999, J NUTR, V129, P602
[9]  
Cesano A, 1998, ANTICANCER RES, V18, P1429
[10]  
Chew BP, 1997, ANTICANCER RES, V17, P1099