Individual and environmental factors associated with infection due to Cryptococcus neoformans serotype D

被引：101

作者：

Dromer, F ^{[1
]}

Mathoulin, S ^{[1
]}

Dupont, B ^{[1
]}

Letenneur, L ^{[1
]}

Ronin, O ^{[1
]}

Chardon, H ^{[1
]}

Hayette, MP ^{[1
]}

Bouchara, P ^{[1
]}

Hautefort, B ^{[1
]}

LePennec, MP ^{[1
]}

Larfouilloux, J ^{[1
]}

Faller, M ^{[1
]}

Reboux, G ^{[1
]}

Couprie, B ^{[1
]}

Bougnoux, ME ^{[1
]}

Masure, O ^{[1
]}

Lefort, C ^{[1
]}

Duhamel, C ^{[1
]}

Zaegel, M ^{[1
]}

Cambon, M ^{[1
]}

Boussougant, Y ^{[1
]}

Bretagne, S ^{[1
]}

Geslin, M ^{[1
]}

Berthelot, M ^{[1
]}

Camerlynck, P ^{[1
]}

Grise, G ^{[1
]}

Gauthier, M ^{[1
]}

Bouchard, I ^{[1
]}

Nauciel, C ^{[1
]}

Lebeau, B ^{[1
]}

Romand, S ^{[1
]}

DesaillyChanson, MA ^{[1
]}

Eloy, O ^{[1
]}

Grillot, ML ^{[1
]}

Boyer, E ^{[1
]}

Gosset, X ^{[1
]}

Bouteille, B ^{[1
]}

Piens, MA ^{[1
]}

Janin, G ^{[1
]}

Tremolieres, F ^{[1
]}

NGuyen, M ^{[1
]}

Eme, A ^{[1
]}

Raspail, P ^{[1
]}

Kures, L ^{[1
]}

Morin, O ^{[1
]}

Felz, M ^{[1
]}

LeFichoux, Y ^{[1
]}

Delage, A ^{[1
]}

Barthez, JP ^{[1
]}

Nouailhat, F ^{[1
]}

机构：

[1] INSERM,BORDEAUX,FRANCE

来源：

CLINICAL INFECTIOUS DISEASES | 1996年 / 23卷 / 01期

关键词：

D O I：

10.1093/clinids/23.1.91

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Differences between the two varieties of Cryptococcus neoformans with regard to geographic distribution, epidemiology, and even pathogenicity have been described, None between C. neoformans variety neoformans serotypes A and D have been reported, We reviewed 452 cases of cryptococcosis diagnosed in France, where serotype D is responsible for 21% of the infections. Univariate analysis showed that the frequency of serotype D infections was significantly higher among patients >60 years of age, those born in Europe, those receiving corticosteroid therapy, and those who had skin lesions, In the multivariate analysis, the risk of serotype D infection was significantly higher for patients with skin lesions, those receiving corticosteroid therapy, and those living in certain regions in France. It was significantly lower for patients with meningitis, those coming from Africa, and females. Among the 350 human immunodeficiency virus-infected patients, the risk was significantly higher for those >60 years old, those who were intravenous drug abusers, and those with skin lesions. The risk was significantly lower for patients from Africa and in cases of meningitis, These results suggest that individual and environmental factors can be associated with the serotype of the infecting strain of C. neoformans.

引用

页码：91 / 96

页数：6

共 30 条

[11] ECOLOGY, LIFE-CYCLE, AND INFECTIOUS PROPAGULE OF CRYPTOCOCCUS-NEOFORMANS
ELLIS, DH
PFEIFFER, TJ
[J]. LANCET, 1990, 336 (8720) : 923 - 925
[12] NATURAL HABITAT OF CRYPTOCOCCUS-NEOFORMANS VAR GATTII
ELLIS, DH
PFEIFFER, TJ
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1990, 28 (07) : 1642 - 1644
[13] MENINGITIS DUE TO CRYPTOCOCCUS-NEOFORMANS BIOVAR GATTII IN A ZAIREAN AIDS PATIENT
KAPENDA, K
KOMICHELO, K
SWINNE, D
VANDEPITTE, J
[J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1987, 6 (03) : 320 - 321
[14] Kwon-Chwag KJ, 1992, MED MYCOL, P397
[15] EPIDEMIOLOGIC DIFFERENCES BETWEEN THE 2 VARIETIES OF CRYPTOCOCCUS-NEOFORMANS
KWONCHUNG, KJ
BENNETT, JE
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1984, 120 (01) : 123 - 130
[16] KWONCHUNG KJ, 1988, P 10 C INT SOC HUM A, P107
[17] LEVITZ SM, 1991, REV INFECT DIS, V13, P1163
[18] WIDE SPECTRUM OF CRYPTOCOCCAL INFECTIONS
LEWIS, JL
RABINOVICH, S
[J]. AMERICAN JOURNAL OF MEDICINE, 1972, 53 (03) : 315 - +
[19] CRYPTOCOCCAL DISEASE OF THE CNS IN IMMUNOCOMPETENT HOSTS - INFLUENCE OF CRYPTOCOCCAL VARIETY ON CLINICAL MANIFESTATIONS AND OUTCOME
MITCHELL, DH
SORRELL, TC
ALLWORTH, AM
HEATH, CH
MCGREGOR, AR
PAPANAOUM, K
RICHARDS, MJ
GOTTLIEB, T
[J]. CLINICAL INFECTIOUS DISEASES, 1995, 20 (03) : 611 - 616
[20] ENVIRONMENTAL ISOLATION OF CRYPTOCOCCUS NEOFORMANS-GATTII FROM CALIFORNIA
PFEIFFER, T
ELLIS, D
[J]. JOURNAL OF INFECTIOUS DISEASES, 1991, 163 (04) : 929 - 930

← 1 2 3 →