Synthesis of 5-, 6- and 7-azaindoles via palladium-catalyzed heteroannulation of internal alkynes

被引：91

作者：

Ujjainwala, F ^{[1
]}

Warner, D ^{[1
]}

机构：

[1] Merck Res Labs, Dept Med Chem, Rahway, NJ 07065 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(98)01069-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed heteroannulation of internal alkynes using ortho-aminoiodopyridine derivatives is described. This experimentally simple procedure, which employs a Pd(dppf)Cl-2/LiCl/Na2CO3 reagent system, allows rapid and reliable access to a structurally diverse range of 5-, 6- and 7-azaindoles. (C) 1998 Elsevier Science Ltd. Air rights reserved.

引用

页码：5355 / 5358

页数：4

共 26 条

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