Fullerene-based amino acids and peptides

被引:101
作者
Bianco, A
Da Ros, T
Prato, M
Toniolo, C
机构
[1] CNRS, Inst Biol Mol & Cellulaire, UPR 9021, Lab Chim Immunol, F-67084 Strasbourg, France
[2] Univ Trieste, Dipartimento Sci Farmaceut, I-34127 Trieste, Italy
[3] Univ Padua, Dipartimento Chim Organ, CNR, Ctr Studio Biopolimeri, I-35100 Padua, Italy
关键词
fulleroamino acids; fulleropeptides; fulleroproline;
D O I
10.1002/psc.313
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent advances in the chemistry of fullerene have allowed the synthesis of many classes of novel fullerene derivatives. Among these classes, fullerene-based amino acids and peptides are particularly interesting, both for structural studies and biological applications. In this review, we mill discuss our own achievements in this rapidly growing field. In particular, the application of fulleroproline (Fpr) amino acids and peptides to medicinal chemistry and material science will be highlighted. Copyright (C) 2001 European Peptide Society and John Wiley & Sons, Ltd.
引用
收藏
页码:208 / 219
页数:12
相关论文
共 73 条
  • [1] SYNTHESIS OF ALPHA-AMINO-ACID DERIVATIVES OF C-60 FROM 1,9-(4-HYDROXYCYCLOHEXANO)-BUCKMINSTERFULLERENE
    AN, YZ
    ANDERSON, JL
    RUBIN, Y
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (18) : 4799 - 4801
  • [2] Bianco A, 1997, J PEPT RES, V50, P159
  • [3] Bianco A, 1998, J PEPT SCI, V4, P364, DOI 10.1002/(SICI)1099-1387(199808)4:5<364::AID-PSC159>3.0.CO
  • [4] 2-O
  • [5] Synthesis, chiroptical properties, and configurational assignment of fulleroproline derivatives and peptides
    Bianco, A
    Maggini, M
    Scorrano, G
    Toniolo, C
    Marconi, G
    Villani, C
    Prato, M
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (17) : 4072 - 4080
  • [6] Molecular recognition by a silica-bound fullerene derivative
    Bianco, A
    Gasparrini, F
    Maggini, M
    Misiti, D
    Polese, A
    Prato, M
    Scorrano, G
    Toniolo, C
    Villani, C
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (32) : 7550 - 7554
  • [7] Bisaglia M, 2000, J NEUROCHEM, V74, P1197
  • [8] Antimycobacterial activity of ionic fullerene derivatives
    Bosi, S
    Da Ros, T
    Castellano, S
    Banfi, E
    Prato, M
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (10) : 1043 - 1045
  • [9] Synthesis of a 1,2-dihydro[60]fullerylglycine derivative by a novel cyclopropane ring opening of a methano[60]fullerene
    Burley, GA
    Keller, PA
    Pyne, SG
    Ball, GE
    [J]. CHEMICAL COMMUNICATIONS, 1998, (22) : 2539 - 2540
  • [10] Antigenicity of fullerenes: Antibodies specific for fullerenes and their characteristics
    Chen, BX
    Wilson, SR
    Das, M
    Coughlin, DJ
    Erlanger, BF
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (18) : 10809 - 10813