In vivo measurements of ultrasound transmission through the human proximal femur

被引：28

作者：

Barkmann, Reinhard ^{[1
]}

Laugier, Pascal ^{[2
]}

Moser, Urs ^{[3
]}

Dencks, Stefanie ^{[1
]}

Klausner, Michael ^{[4
]}

Padilla, Frederic ^{[2
]}

Haiat, Guillaume ^{[5
]}

Heller, Martin

Glueer, Claus-C. ^{[1
]}

机构：

[1] Univ Klinikum Schleswig Holstein, D-24220 Kiel, Germany

[2] Univ Paris 06, CNRS, UMR 7623, Lab Imagerie Parametr, Paris, France

[3] Sulzer Innotec, Winterthur, Switzerland

[4] FB Maschinenwesen, Fachsch Kiel, Kiel, Germany

[5] Univ Paris 12, Mecan Phys Lab, CNRS, UMR 7052,B2OA, Creteil, France

来源：

ULTRASOUND IN MEDICINE AND BIOLOGY | 2008年 / 34卷 / 07期

关键词：

quantitative ultrasound; femur; fracture risk;

D O I：

10.1016/j.ultrasmedbio.2007.12.008

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Quantitative ultrasound (QUS) measurements can be used to estimate osteoporotic fracture risk. The commonly used variables are the speed of sound (SOS) and the frequency dependent sound attenuation (broadband ultrasound attenuation, [BUA]) of a wave propagating through the bone, preferably the calcaneus. The technology, so far, is less suitable for direct measurement in vivo at the spine or the femur for prediction of bone mineral density (BMD) or fracture risk at the main osteoporotic fracture sites. To improve the clinical performance of QUS, we built a device for direct QUS measurements at the human femur in vivo. In vivo images of ultrasound transmission at one of the main fracture sites, the proximal femur, could be acquired. The estimated precision of SOS measurements of 0.5% achieved at the femur is comparable with the precision of peripheral QUS devices. (E-mail: barkmann@rad.uni-kiel.de) (C) 2008 World Federation for Ultrasound in Medicine & Biology.

引用

页码：1186 / 1190

页数：5

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