Continuous sample rotation data collection for protein crystallography with the PILATUS detector

被引:34
作者
Brönnimann, C [1 ]
Eikenberry, EF
Horisberger, R
Hülsen, G
Schmitt, B
Schulze-Briese, C
Tomizaki, T
机构
[1] Paul Scherrer Inst, WSLA 218, SLS, CH-5232 Villigen, Switzerland
[2] Paul Scherrer Inst, CH-5232 Villigen, Switzerland
关键词
protein crystallography; single-photon counting; fine phi-slicing; continuous sample rotation;
D O I
10.1016/S0168-9002(03)01673-5
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
The PILATUS detector (pixel apparatus for the SLS) is a large all silicon quantum-limited area X-ray detector for protein crystallography. A three-module array with 1120 x 157 pixels covering an active area of 24.3 x 3.6 cm(2) is in operation. Its main features are an excellent point-spread function, a very high dynamic range and, 4 readout time of < 7 ms. X-rays with energy above 6 keV can be detected in single photon counting mode. To demonstrate the potential of the detector, fine phi-sliced protein crystal data were collected in continuous sample rotation mode at beamline X06SA of the SLS. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:24 / 28
页数:5
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