A high yield semisynthetic approach to 2'-epi-taxol

被引：8

作者：

Cabri, W ^{[1
]}

Curini, M ^{[1
]}

Marcotullio, MC ^{[1
]}

Rosati, O ^{[1
]}

机构：

[1] UNIV PERUGIA,FAC FARM,IST CHIM ORGAN,I-06123 PERUGIA,ITALY

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 27期

关键词：

D O I：

10.1016/0040-4039(96)00935-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new 2-steps synthesis of 2'-epi-Taxol starting from natural Taxol(R) is described. The approach is centred on the formation of oxazoline on the side chain with concomitant inversion of the C-2' followed by acid hydrolysis. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：4785 / 4786

页数：2

共 7 条

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[J]. TETRAHEDRON LETTERS, 1994, 35 (43) : 7893 - 7896
[6] SYNTHESIS OF TAXOL FROM BACCATIN-3 VIA AN OXAZOLINE INTERMEDIATE
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[J]. TETRAHEDRON LETTERS, 1994, 35 (26) : 4483 - 4484
[7] CHEMISTRY AND BIOLOGY OF TAXOL
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[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1994, 33 (01) : 15 - 44

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