Facultative to strict anaerobes ratio in the preterm infant microbiota A target for intervention?

被引：52

作者：

Arboleya, Silvia ^{[1
]}

Solis, Gonzalo ^{[2
]}

Fernandez, Nuria ^{[3
]}

de los Reyes-Gavilan, Clara G. ^{[1
]}

Gueimonde, Miguel ^{[1
]}

机构：

[1] CSIC, IPLA, Dept Microbiol & Biochem, Villaviciosa, Asturias, Spain

[2] Hosp Univ Cent Asturias, Paediat Serv, Serv Salud Principado Asturias, Oviedo, Asturias, Spain

[3] Hosp Cabuenes, Paediat Serv, Serv Salud Principado Asturias, Gijon, Asturias, Spain

来源：

GUT MICROBES | 2012年 / 3卷 / 06期

关键词：

preterm neonates; infants; intestinal microbiota; anaerobes; facultative anaerobes;

D O I：

10.4161/gmic.21942

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

During recent years there has been an increasing interest on the development of strategies for modulating the process of microbiota establishment in preterm infants. For successfully developing of such strategies, a detailed knowledge of the microbiota establishment process in these infants is needed. In a previous study we evidenced clear alterations in the process of microbiota establishment in preterm newborns when compared with a control group of full-term breast-fed infants. Here we have analyzed these data more in depth, corroborating a reduced proportion of strict anaerobes with respect to facultatives in the fecal microbiota of preterm infants. The potential benefits, as well as the side effects, of strategies aimed at counterbalancing this alteration in the facultative to strict anaerobes ratio are discussed in this addendum.

引用

页码：583 / 588

页数：6

共 40 条

[1]

AlFaleh K, 2011, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD005496.pub3, 10.1097/AOG.0b013e3181726f2f]

[2] Establishment and development of intestinal microbiota in preterm neonates [J].

Arboleya, Silvia ;

Binetti, Ana ;

Salazar, Nuria ;

Fernandez, Nuria ;

Solis, Gonzalo ;

Hernandez-Barranco, Ana ;

Margolles, Abelardo ;

de los Reyes-Gavilan, Clara G. ;

Gueimonde, Miguel .

FEMS MICROBIOLOGY ECOLOGY, 2012, 79 (03) :763-772

[3] Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial [J].

Besselink, Marc G. H. ;

van Santvoort, Hjalmar C. ;

Buskens, Erik ;

Boermeester, Marja A. ;

van Goor, Harry ;

Timmerman, Harro M. ;

Nieuwenhuijs, Vincent B. ;

Bollen, Thomas L. ;

van Ramshorst, Bert ;

Witteman, Ben J. M. ;

Rosman, Camiel ;

Ploeg, Rutger J. ;

Brink, Menno A. ;

Schaapherder, Alexander F. M. ;

Dejong, Cornelis H. C. ;

Wahab, Peter J. ;

van Laarhoven, Cees J. H. M. ;

van der Harst, Erwin ;

van Eijck, Casper H. J. ;

Cuesta, Miguel A. ;

Akkermans, Louis M. A. ;

Gooszen, Hein G. .

LANCET, 2008, 371 (9613) :651-659

[4] Oral probiotics prevent necrotizing enterocolitis in very low birth weight neonates [J].

Bin-Nun, A ;

Bromiker, R ;

Wilschanski, M ;

Kaplan, M ;

Rudensky, B ;

Caplan, M ;

Hammerman, C .

JOURNAL OF PEDIATRICS, 2005, 147 (02) :192-196

[5] The long-term health effects of neonatal microbial flora [J].

Conroy, Michelle E. ;

Shi, Hai Ning ;

Walker, W. Allan .

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 9 (03) :197-201

[6] Maturation of the antioxidant system and the effects on preterm birth [J].

Davis, Jonathan M. ;

Auten, Richard L. .

SEMINARS IN FETAL & NEONATAL MEDICINE, 2010, 15 (04) :191-195

[7] Updated Meta-analysis of Probiotics for Preventing Necrotizing Enterocolitis in Preterm Neonates [J].

Deshpande, Girish ;

Rao, Shripada ;

Patole, Sanjay ;

Bulsara, Max .

PEDIATRICS, 2010, 125 (05) :921-930

[8] Evidence-based guidelines for use of probiotics in preterm neonates [J].

Deshpande, Girish C. ;

Rao, Shripada C. ;

Keil, Anthony D. ;

Patole, Sanjay K. .

BMC MEDICINE, 2011, 9

[9] Role of the Host Defense System and Intestinal Microbial Flora in the Pathogenesis of Necrotizing Enterocolitis [J].

Emami, Claudia N. ;

Petrosyan, Mikael ;

Giuliani, Stefano ;

Williams, Monica ;

Hunter, Catherine ;

Prasadarao, Nemani V. ;

Ford, Henri R. .

SURGICAL INFECTIONS, 2009, 10 (05) :407-417

[10] A Summary of the Agency for Healthcare Research and Quality's Evidence Report on Breastfeeding in Developed Countries [J].

Ip, Stanley ;

Chung, Mei ;

Raman, Gowri ;

Trikalinos, Thomas A. ;

Lau, Joseph .

BREASTFEEDING MEDICINE, 2009, 4 :S17-S30

← 1 2 3 4 →