Regulation of the Apaf-1-caspase-9 apoptosome

被引：335

作者：

Bratton, Shawn B. ^{[1
,2
,3
]}

Salvesen, Guy S. ^{[4
]}

机构：

[1] Univ Texas Austin, Div Pharmacol & Toxicol, Coll Pharm, Austin, TX 78712 USA

[2] Univ Texas Austin, Ctr Mol & Cellular Toxicol, Austin, TX 78712 USA

[3] Univ Texas Austin, Inst Cellular & Mol Biol, Austin, TX 78712 USA

[4] Sanford Burnham Med Res Inst, Program Apoptosis & Cell Death Res, La Jolla, CA 92037 USA

来源：

JOURNAL OF CELL SCIENCE | 2010年 / 123卷 / 19期

关键词：

DEATH PROTEASE CASPASE-9; C-DEPENDENT ACTIVATION; CYTOCHROME-C; CELL-DEATH; APAF-1; APOPTOSOME; NUCLEOTIDE EXCHANGE; NEGATIVE REGULATION; INHIBITS APOPTOSIS; PROVIDES INSIGHTS; PHOSPHORYLATION;

D O I：

10.1242/jcs.073643

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

[No abstract available]

引用

页码：3209 / 3214

页数：6

共 64 条

[41] Dimer formation drives the activation of the cell death protease caspase 9 [J].

Renatus, M ;

Stennicke, HR ;

Scott, FL ;

Liddington, RC ;

Salvesen, GS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (25) :14250-14255

[42] Structure of the apoptotic protease-activating factor 1 bound to ADP [J].

Riedl, SJ ;

Li, WY ;

Chao, Y ;

Schwarzenbacher, R ;

Shi, YG .

NATURE, 2005, 434 (7035) :926-933

[43]

Riedl SJ, 2001, CELL, V104, P791, DOI 10.1016/S0092-8674(01)00274-4

[44] The apoptosome: signalling platform of cell death [J].

Riedl, Stefan J. ;

Salvesen, Guy S. .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2007, 8 (05) :405-413

[45] Caspase-9 and APAF-1 form an active holoenzyme [J].

Rodriguez, J ;

Lazebnik, Y .

GENES & DEVELOPMENT, 1999, 13 (24) :3179-3184

[46] Proapoptotic histone H1.2 induces CASP-3 and -7 activation by forming a protein complex with CYT c, APAF-1 and CASP-9 [J].

Ruiz-Vela, Antonio ;

Korsmeyer, Stanley J. .

FEBS LETTERS, 2007, 581 (18) :3422-3428

[47] Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis [J].

Sakai, T ;

Liu, L ;

Teng, XC ;

Mukai-Sakai, R ;

Shimada, H ;

Kaji, R ;

Mitani, T ;

Matsumoto, M ;

Toida, K ;

Ishimura, K ;

Shishido, Y ;

Mak, TW ;

Fukui, K .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (39) :41131-41140

[48] Negative regulation of the Apaf-1 apoptosome by Hsp70 [J].

Saleh, A ;

Srinivasula, SM ;

Balkir, L ;

Robbins, PD ;

Alnemri, ES .

NATURE CELL BIOLOGY, 2000, 2 (08) :476-483

[49] The Fas-FADD death domain complex structure unravels signalling by receptor clustering [J].

Scott, Fiona L. ;

Stec, Boguslaw ;

Pop, Cristina ;

Dobaczewska, Malgorzata K. ;

Lee, JeongEun J. ;

Monosov, Edward ;

Robinson, Howard ;

Salvesen, Guy S. ;

Schwarzenbacher, Robert ;

Riedl, Stefan J. .

NATURE, 2009, 457 (7232) :1019-1022

[50] XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs [J].

Scott, FL ;

Denault, JB ;

Riedl, SJ ;

Shin, H ;

Renatus, M ;

Salvesen, GS .

EMBO JOURNAL, 2005, 24 (03) :645-655

← 1 2 3 4 5 6 7 →