Human coronavirus NL63 associated with lower respiratory tract symptoms in early life

被引：56

作者：

Kaiser, L ^{[1
]}

Regamey, N

Roiha, H

Deffernez, C

Frey, U

机构：

[1] Univ Hosp Geneva, Div Infect Dis, Cent Lab Virol, Geneva, Switzerland

[2] Univ Hosp, Inselspital, Dept Pediat, Bern, Switzerland

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2005年 / 24卷 / 11期

关键词：

coronavirus; coronavirus NL63; respiratory viral infections; infants; respiratory tract infections;

D O I：

10.1097/01.inf.0000183773.80217.12

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Coronavirus NL63 has been identified as a new member of the coronavirus genus, but its role as a cause of respiratory disease needs to be established. We studied the first episode of lower respiratory tract symptoms in a cohort of healthy neonates. NL63 was identified in 6 (7%) of 82 cases and was as frequent as other coronaviruses (9%). NL63 was recovered at the onset of symptoms and was cleared within 3 weeks in half of the cases. Our data suggests that coronavirus NL63 causes lower respiratory tract symptoms and is acquired in early life.

引用

页码：1015 / 1017

页数：3

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