The action of low-intensity pulsed ultrasound in bones of osteopenic rats

被引:20
作者
Carvalho, DCL
Cliquet, A
机构
[1] Univ Sao Paulo, Post Grad Course Unit, EESC,FMRP,IQSC, BR-05508 Sao Paulo, Brazil
[2] Univ Sao Paulo, Bioengn Inter Unit, EESC,FMRP,IQSC, BR-05508 Sao Paulo, Brazil
[3] Univ Sao Paulo, SEL,EESC, Sch Engn Sao Carlos, Dept Elect Engn, BR-05508 Sao Paulo, Brazil
[4] Univ Campinas, DOT, UNICAMP, Orthopaed & Traumatol Dept, Campinas, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
low-intensity ultrasound; rat model; osteopenia; calcium and phosphorus analysis; structural analysis;
D O I
10.1111/j.1525-1594.2004.07091.x
中图分类号
R318 [生物医学工程];
学科分类号
0831 [生物医学工程];
摘要
In this study, the action of low-intensity pulsed ultrasound for 20 min/day, during twenty days, was analyzed in an attempt to revert bone loss in the proximal femur of osteopenic rats. Although the quantitative results of bone mineral content (BMC) demonstrated no significant difference among the groups ( P > 0.05), the histologic investigations have shown the occurrence of recent bone formation not observed in the nontreated group. Moreover, the treated femur presented less microarchitectural deterioration than the nontreated group. These results suggest that the low-intensity ultrasound can interfere in a positive way on osteoporosis.
引用
收藏
页码:114 / 118
页数:5
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