Marked improvement of severe progressive systemic sclerosis after transplantation of mesenchymal stem cells from an allogeneic haploidentical-related donor mediated by ligation of CD137L

被引:128
作者
Christopeit, M. [1 ]
Schendel, M. [2 ]
Foell, J. [3 ]
Mueller, L. P. [1 ]
Keysser, G. [2 ]
Behre, G. [1 ]
机构
[1] Univ Hosp Halle, Bone Marrow Transplantat Unit, Dept Internal Med 4, Halle, Germany
[2] Univ Hosp Halle, Dept Internal Med 1, Halle, Germany
[3] Univ Hosp Halle, Dept Pediat, Halle, Germany
关键词
D O I
10.1038/sj.leu.2404996
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
引用
收藏
页码:1062 / 1064
页数:5
相关论文
共 5 条
[1]
Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion [J].
Devine, SM ;
Bartholomew, AM ;
Mahmud, N ;
Nelson, M ;
Patil, S ;
Hardy, W ;
Sturgeon, C ;
Hewett, T ;
Chung, T ;
Stock, W ;
Sher, D ;
Weissman, S ;
Ferrer, K ;
Mosca, J ;
Deans, R ;
Moseley, A ;
Hoffman, R .
EXPERIMENTAL HEMATOLOGY, 2001, 29 (02) :244-255
[2]
Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta [J].
Le Blanc, K ;
Götherström, C ;
Ringdén, O ;
Hassan, M ;
McMahon, R ;
Horwitz, E ;
Anneren, G ;
Axelsson, O ;
Nunn, J ;
Ewald, U ;
Nordén-Lindeberg, S ;
Jansson, M ;
Dalton, A ;
Åström, E ;
Westgren, M .
TRANSPLANTATION, 2005, 79 (11) :1607-1614
[3]
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells [J].
Le Blanc, K ;
Rasmusson, I ;
Sundberg, B ;
Götherström, C ;
Hassan, M ;
Uzunel, M ;
Ringdén, O .
LANCET, 2004, 363 (9419) :1439-1441
[4]
Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease [J].
Sun, YL ;
Chen, HM ;
Subudhi, SK ;
Chen, J ;
Koka, R ;
Chen, LP ;
Fu, YX .
NATURE MEDICINE, 2002, 8 (12) :1405-1413
[5]
Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy [J].
Zappia, E ;
Casazza, S ;
Pedemonte, E ;
Benvenuto, F ;
Bonanni, I ;
Gerdoni, E ;
Giunti, D ;
Ceravolo, A ;
Cazzanti, F ;
Frassoni, F ;
Mancardi, G ;
Uccelli, A .
BLOOD, 2005, 106 (05) :1755-1761