New Options in the Therapeutic Management of Acute Ischaemic Stroke. Good Results with Combined i.v. and i.a. Lysis and Mechanical Thrombectomy

被引：8

作者：

Venker, C. ^{[1
]}

Stracke, P. ^{[2
]}

Berlit, P. ^{[1
]}

Diehl, R. R. ^{[1
]}

Kurre, W. ^{[2
]}

Sorgenfrei, U. ^{[1
]}

Kraemer, M. ^{[1
]}

Chapot, R. ^{[2
]}

机构：

[1] Alfried Krupp Hosp, Neurol Klin, D-45131 Essen, Germany

[2] Alfried Krupp Hosp, Klin Neuroradiol, D-45131 Essen, Germany

来源：

FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE | 2010年 / 78卷 / 11期

关键词：

stroke; thrombolysis; thrombectomy; recanalisation; Solitaire FR stent; THROMBOLYSIS; EMBOLECTOMY; ALTEPLASE; ARTERY;

D O I：

10.1055/s-0029-1245582

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Standard therapy for acute ischaemic stroke is the intravenous thrombolysis with rtPA. A combined therapy with intravenous bridging and consecutive intraarterial thrombolysis and mechanical thrombectomy is a relatively new option in patients with proximal vessel occlusion. Patients and Methods: 10 Patients with a CTA proven proximal vessel occlusion in the anterior circulation (Ad, carotis bifurcation, MCA) in CTA were treated with a combined therapy with i.v. and i.a. thrombolysis and thrombectomy with a Solitaire FR stent device. Results: All Patients were recanalized, the NIHSS changed from 15.6 to 3.3. 8 out of 10 patients had nearly no symptoms when dismissed. There were no direct therapeutic complications. Conclusion: Combined therapy with i.v. and i.a. thrombolysis and thombectomy with the Solitaire FR stent device is a promising option in patients with acute proximal vessel occlusion in the anterior circulation.

引用

页码：652 / 657

页数：6

共 19 条

[11] Comparison of intraarterial and intravenous thrombolysis for ischemic stroke with hyperdense middle cerebral artery sign [J].

Mattle, Heinrich P. ;

Arnold, Marcel ;

Georgiadis, Dimitrios ;

Baumann, Christian ;

Nedeltchev, Krassen ;

Benninger, David ;

Remonda, Luca ;

von Buedingen, Christian ;

Diana, Anca ;

Pangalu, Athina ;

Schroth, Gerhard ;

Baumgartner, Ralf W. .

STROKE, 2008, 39 (02) :379-383

[12]

MCDOUGALL C, 2008, 2008 P INT STROK C F

[13] Endovascular Approaches to Acute Stroke, Part 2: A Comprehensive Review of Studies and Trials [J].

Nogueira, R. G. ;

Yoo, A. J. ;

Buonanno, F. S. ;

Hirsch, J. A. .

AMERICAN JOURNAL OF NEURORADIOLOGY, 2009, 30 (05) :859-875

[14] The impact of recanalization on ischemic stroke outcome - A meta-analysis [J].

Rha, Joung-Ho ;

Saver, Jeffrey L. .

STROKE, 2007, 38 (03) :967-973

[15] Need to Clarify Thrombolysis In Myocardial Ischemia (TIMI) Scale Scoring Method in the Penumbra Pivotal Stroke Trial [J].

Saver, Jeffrey L. ;

Liebeskind, David S. ;

Nogueira, Raul G. ;

Jahan, Reza .

STROKE, 2010, 41 (02) :E115-E116

[16] Mechanical thrombectomy for acute ischemic stroke - Final results of the multi MERCI trial [J].

Smith, Wade S. ;

Sung, Gene ;

Saver, Jeffrey ;

Budzik, Ronald ;

Duckwiler, Gary ;

Liebeskind, David S. ;

Lutsep, Helmi L. ;

Rymer, Marilyn M. ;

Higashida, Randall T. ;

Starkman, Sidney ;

Gobin, Y. Pierre .

STROKE, 2008, 39 (04) :1205-1212

[17] Safety and efficacy of mechanical embolectomy in acute ischemic stroke - Results of the MERCI trial [J].

Smith, WS ;

Sung, G ;

Starkman, S ;

Saver, JL ;

Kidwell, CS ;

Gobin, YP ;

Lutsep, HL ;

Nesbit, GM ;

Grobelny, T ;

Rymer, MM ;

Silverman, IE ;

Higashida, RT ;

Budzik, RF ;

Marks, MP .

STROKE, 2005, 36 (07) :1432-1438

[18]

Wikholm G, 2003, AM J NEURORADIOL, V24, P892

[19]

Wolfe Thomas, 2008, J Stroke Cerebrovasc Dis, V17, P121, DOI 10.1016/j.jstrokecerebrovasdis.2007.12.004

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