Tree nut allergens

被引:144
作者
Roux, KH
Teuber, SS
Sathe, K
机构
[1] Florida State Univ, Dept Biol Sci, Biol Unit 1, Tallahassee, FL 32306 USA
[2] Florida State Univ, Inst Mol Biophys, Tallahassee, FL 32306 USA
[3] Florida State Univ, Dept Nutr Food & Exercise Sci, Tallahassee, FL 32306 USA
[4] Univ Calif Davis, Sch Med, Dept Internal Med, Davis, CA 95616 USA
关键词
tree nuts; allergen;
D O I
10.1159/000072135
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Allergic reactions to tree nuts can be serious and life threatening. Considerable research has been conducted in recent years in an attempt to characterize those allergens that are most responsible for allergy sensitization and triggering: Both native and recombinant nut allergens have been identified and characterized and, for some, the IgE-reactive epitopes described. Some allergens, such as lipid transfer proteins, profilins, and members of the Bet v 1-related family, represent minor constituents in tree nuts. These allergens are frequently cross-reactive with other food and pollen homologues, and are considered panallergens. Others, such as legumins, vicilins, and 2S albumins, represent major seed storage protein constituents of the nuts. The allergenic tree nuts discussed in this review include those most commonly responsible for allergic reactions such as hazelnut, walnut, cashew, and almond as well as those less frequently associated with allergies including pecan, chestnut, Brazil nut, pine nut, macadamia nut, pistachio, coconut, Nangai nut, and acorn. Copyright (C) 2003 S. Karger AG, Basel.
引用
收藏
页码:234 / 244
页数:11
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