New frontiers in nanotechnology for cancer treatment

被引：309

作者：

Alexis, Frank ^{[1
,3
,4
]}

Rhee, June-Wha ^{[1
,3
,4
]}

Richie, Jerome P. ^{[2
,3
]}

Radovic-Moreno, Aleksandar F. ^{[4
,5
,6
]}

Langer, Robert ^{[4
,5
,6
]}

Farokhzad, Omid C. ^{[1
,3
,4
]}

机构：

[1] Brigham & Womens Hosp, Dept Anesthesiol, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Dept Urol, Boston, MA 02115 USA

[3] Harvard Univ, Sch Med, Boston, MA 02115 USA

[4] MIT, Harvard Ctr Canc Nanotechno Excellence, Cambridge, MA 02139 USA

[5] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

[6] Harvard Univ, MIT, Div Hlth Sci & Technol, Boston, MA 02115 USA

来源：

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS | 2008年 / 26卷 / 01期

关键词：

cancer therapy; cancer diagnosis; nanocarriers; targeting molecules;

D O I：

10.1016/j.urolonc.2007.03.017

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Nanotechnology is a field of research at the crossroads of biology, chemistry, physics, engineering, and medicine. Design of multifunctional nanoparticles capable of targeting cancer cells, delivering and releasing drugs in a regulated manner, and detecting cancer cells with enormous specificity and sensitivity are just some examples of the potential application of nanotechnology to oncological diseases. In this review we discuss the recent advances of cancer nanotechnology with particular attention to nanoparticle systems that are in clinical practice or in various stages of development for cancer imaging and therapy. Published by Elsevier Inc.

引用

页码：74 / 85

页数：12

共 152 条

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