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NKT cells: facts, functions and fallacies

被引：704
作者：
Godfrey, DI
Hammond, KJL
Poulton, LD
Smyth, MJ
Baxter, AG
机构：
[1] Monash Univ, Sch Med, Dept Pathol & Immunol, Prahran, Vic 3181, Australia
[2] Centenary Inst Canc Med & Cell Biol, Newtown, NSW 2042, Australia
来源：
IMMUNOLOGY TODAY | 2000年 / 21卷 / 11期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/S0167-5699(00)01735-7
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The proposed roles of NK1.1(+) T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, wherever possible, to compare what is known about NKT-cell subsets.
引用
收藏
页码：573 / 583
页数：11
相关论文
共 127 条
  • [1] Evidence for two subgroups of CD4-CD8- NKT cells with distinct TCRαβ repertoires and differential distribution in lymphoid tissues
    Apostolou, I
    Cumano, A
    Gachelin, G
    Kourilsky, P
    [J]. JOURNAL OF IMMUNOLOGY, 2000, 165 (05) : 2481 - 2490
  • [2] Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls
    Apostolou, I
    Takahama, Y
    Belmant, C
    Kawano, T
    Huerre, M
    Marchal, G
    Cui, J
    Taniguchi, M
    Nakauchi, H
    Fournié, JJ
    Kourilsky, P
    Gachelin, G
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (09) : 5141 - 5146
  • [3] CYTOTOXICITY OF FRESH NK1.1(+) T-CELL RECEPTOR ALPHA/BETA(+) THYMOCYTES AGAINST A CD4+8+ THYMOCYTE POPULATION ASSOCIATED WITH INTACT FAS ANTIGEN EXPRESSION ON THE TARGET
    ARASE, H
    ARASE, N
    KOBAYASHI, Y
    NISHIMURA, Y
    YONEHARA, S
    ONOE, K
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 180 (02) : 423 - 432
  • [4] Interferon gamma production by natural killer (NK) cells and NK1.1(+) T cells upon NKR-P1 cross-linking
    Arase, H
    Arase, N
    Saito, T
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (05) : 2391 - 2396
  • [5] Association between alpha beta TCR(+)CD4(-)CD8(-) T-cell deficiency and IDDM in NOD/Lt mice
    Baxter, AG
    Kinder, SJ
    Hammond, KJL
    Scollay, R
    Godfrey, DI
    [J]. DIABETES, 1997, 46 (04) : 572 - 582
  • [6] Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis
    Behar, SM
    Dascher, CC
    Grusby, MJ
    Wang, CR
    Brenner, MB
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (12) : 1973 - 1980
  • [7] MOUSE NK1(+) T-CELLS
    BENDELAC, A
    [J]. CURRENT OPINION IN IMMUNOLOGY, 1995, 7 (03) : 367 - 374
  • [8] Mouse CD1-specific NK1 T cells: Development, specificity, and function
    Bendelac, A
    Rivera, MN
    Park, SH
    Roark, JH
    [J]. ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 : 535 - 562
  • [9] A SUBSET OF CD4(+) THYMOCYTES SELECTED BY MHC CLASS-I MOLECULES
    BENDELAC, A
    KILLEEN, N
    LITTMAN, DR
    SCHWARTZ, RH
    [J]. SCIENCE, 1994, 263 (5154) : 1774 - 1778
  • [10] Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1T cells
    Bendelac, A
    Hunziker, RD
    Lantz, O
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (04) : 1285 - 1293
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