NKT cells: facts, functions and fallacies

被引:704
作者
Godfrey, DI
Hammond, KJL
Poulton, LD
Smyth, MJ
Baxter, AG
机构
[1] Monash Univ, Sch Med, Dept Pathol & Immunol, Prahran, Vic 3181, Australia
[2] Centenary Inst Canc Med & Cell Biol, Newtown, NSW 2042, Australia
来源
IMMUNOLOGY TODAY | 2000年 / 21卷 / 11期
基金
英国医学研究理事会;
关键词
D O I
10.1016/S0167-5699(00)01735-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The proposed roles of NK1.1(+) T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, wherever possible, to compare what is known about NKT-cell subsets.
引用
收藏
页码:573 / 583
页数:11
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