Possible origin for porphin derivatives in prebiotic chemistry - A computational study

被引：22

作者：

Aylward, N ^{[1
]}

Bofinger, N ^{[1
]}

机构：

[1] Queensland Univ Technol, Sch Nat Resource Sci, Brisbane, Qld 4000, Australia

来源：

ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES | 2005年 / 35卷 / 04期

关键词：

origins of porphyrins; prebiotic availability of photosynthetic pigments; prebiotic chemistry; theoretical chemistry;

D O I：

10.1007/s11084-005-2044-x

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A set of chemical reactions is postulated to account for the formation of the macrocyclic porphin structure, basic to the pyrrole derivatives chlorophyll, protoporphyrin, heme and bilirubin, important in photosynthesis, respiration and digestion. A set of equations is given for the prebiotic synthesis of porphin derivatives from the simple molecules; cyanoacetylene, diacetylene, carbon monoxide and ammonia that have been detected in space. A number of isomers of hydrogenated porphin arise which may lose hydrogen to give ultimately porphin and its dehydrogenated derivative. The reactions, while not unique, provide a pathway which has been shown to be feasible from the overall enthalpy changes in the ZKE approximation at the HF and MP2/6-31G* level.

引用

页码：345 / 368

页数：24