Rebomer retrieves Wntless

被引：70

作者：

Eaton, Suzanne ^{[1
]}

机构：

[1] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany

来源：

DEVELOPMENTAL CELL | 2008年 / 14卷 / 01期

关键词：

D O I：

10.1016/j.devcel.2007.12.014

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Wntless is a sorting receptor required for Wnt secretion. Wntless is retrieved from endosomes to the Golgi by retromer, permitting Wntless reutilization in Wnt transport. In the absence of retromer, Wntless is degraded in lysosomes and Wnt secretion is impaired.

引用

页码：4 / 6

页数：3

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