A new simple route to N-substituted 2-aminoethylphosphonic acids

被引：19

作者：

Fu, XK ^{[1
]}

Gong, CB ^{[1
]}

Ma, XB ^{[1
]}

Wen, SY ^{[1
]}

机构：

[1] SW China Normal Univ, Coll Chem & Chem Engn, Chongqing 400715, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 14期

关键词：

D O I：

10.1080/00397919808004835

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Aminoethylphosphonic acid (AEPA) and its N-substituted compounds were prepared by one step reaction using 2-chloroethylphosphonic acid with ammonia and amines (H2NMe, HNMeMe, HMEtEt, H2NPr-n, H(2)NCH(2)ph,H2NCH2CH2NH2 and H2N(C=NII)NH2 in a dilute alkaline solution below 20 degrees C with simple work-up and easy purification. The reaction was accelerated by catalytic amount of potassium iodide. The yield for the reaction products were 35.6 to 48.6% for the KI absence and 78.2 to 88.0% for the KI presence.

引用

页码：2659 / 2664

页数：6

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