Heparin-induced thrombocytopenia in neurologic patients treated with low-molecular-weight heparin

被引：20

作者：

Pohl, C

Kredteck, A

Bastians, B

Hanfland, P

Klockgether, T

Harbrecht, U

机构：

[1] Univ Hosp Bonn, Inst Expt Hematol & Transfus Med, D-53105 Bonn, Germany

[2] Univ Hosp Bonn, Dept Neurol, D-53105 Bonn, Germany

来源：

NEUROLOGY | 2005年 / 64卷 / 07期

关键词：

D O I：

10.1212/01.WNL.0000156947.45112.16

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors prospectively studied the risk for immune-mediated heparin-induced thrombocytopenia (HIT) in neurologic patients during administration of low-molecular-weight heparin (LMWH) vs unfractionated heparin (UFH). None of 111 neurologic patients receiving LMWH developed HIT, whereas HIT occurred in 2.5% of 200 patients treated with UFH (p = 0.17). The rate of heparin-induced antibodies in patients treated with LMWH was lower than in patients treated with UFH (1.8 vs 20.5%; p < 0.001).

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页码：1285 / 1287

页数：3

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