290 and 340 nm UV LED arrays for fluorescence detection from single airborne particles

被引:87
作者
Davitt, K [1 ]
Song, YK
Patterson, WR
Nurmikko, AV
Gherasimova, M
Han, J
Pan, YL
Chang, RK
机构
[1] Brown Univ, Div Engn, Providence, RI 02912 USA
[2] Yale Univ, Dept Elect Engn, New Haven, CT 06520 USA
[3] Yale Univ, Dept Appl Phys, New Haven, CT 06520 USA
[4] Ctr Laser Diagnost, New Haven, CT 06520 USA
来源
OPTICS EXPRESS | 2005年 / 13卷 / 23期
关键词
D O I
10.1364/OPEX.13.009548
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We demonstrate a compact system, incorporating a 32-element linear array of ultraviolet (290 nm and 340 nm) light-emitting diodes (LEDs) and a multi-anode photomultiplier tube, to the in-flight fluorescence detection of aerosolized particles, here containing the biological molecules tryptophan and NADH. This system illustrates substantial advances in the growth and fabrication of new semiconductor UV light emitting devices and an evolution in packaging details for LEDs tailored to the bio-aerosol warning problem. Optical engineering strategies are employed which take advantage of the size and versatility of light-emitting diodes to develop a truly compact fluorescence detector. (c) 2005 Optical Society of America.
引用
收藏
页码:9548 / 9555
页数:8
相关论文
共 16 条
[1]   High-power deep ultraviolet light-emitting diodes based on a micro-pixel design [J].
Adivarahan, V ;
Wu, S ;
Sun, WH ;
Mandavilli, V ;
Shatalov, MS ;
Simin, G ;
Yang, JW ;
Maruska, HP ;
Khan, MA .
APPLIED PHYSICS LETTERS, 2004, 85 (10) :1838-1840
[2]  
Bottiger J. R., 1999, US Patent, Patent No. [5,918,254, 5918254]
[3]   Differences in detected fluorescence among several bacterial species measured with a direct-reading particle sizer and fluorescence detector [J].
Brosseau, LM ;
Vesley, D ;
Rice, N ;
Goodell, K ;
Nellis, M ;
Hairston, P .
AEROSOL SCIENCE AND TECHNOLOGY, 2000, 32 (06) :545-558
[4]   Design of an instrument for real-time detection of bioaerosols using simultaneous measurement of particle aerodynamic size and intrinsic fluorescence [J].
Hairston, PP ;
Ho, J ;
Quant, FR .
JOURNAL OF AEROSOL SCIENCE, 1997, 28 (03) :471-482
[5]  
Hill SC, 1999, FIELD ANAL CHEM TECH, V3, P221, DOI 10.1002/(SICI)1520-6521(1999)3:4/5<221::AID-FACT2>3.0.CO
[6]  
2-7
[7]   Fluorescence from airborne microparticles: dependence on size, concentration of fluorophores, and illumination intensity [J].
Hill, SC ;
Pinnick, RG ;
Niles, S ;
Fell, NF ;
Pan, YL ;
Bottiger, J ;
Bronk, BV ;
Holler, S ;
Chang, RK .
APPLIED OPTICS, 2001, 40 (18) :3005-3013
[8]   High performance AlGaInN ultraviolet light-emitting diode at the 340 nm wavelength [J].
Jeon, SR ;
Gherasimova, M ;
Ren, ZY ;
Su, J ;
Cui, G ;
Han, J ;
Peng, HB .
JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS & EXPRESS LETTERS, 2004, 43 (11A) :L1409-L1412
[9]   Single particle multichannel bio-aerosol fluorescence sensor [J].
Kaye, PH ;
Stanley, WR ;
Hirst, E ;
Foot, EV ;
Baxter, KL ;
Barrington, SJ .
OPTICS EXPRESS, 2005, 13 (10) :3583-3593
[10]  
Lakowicz J.R., 2004, PRINCIPLES FLUORESCE, V3rd