Novel approaches to the treatment of cachexia

被引：41

作者：

Argiles, Josep M. ^{[1
]}

Lopez-Soriano, Franco J. ^{[1
]}

Busquets, Silvia ^{[1
]}

机构：

[1] Univ Barcelona, Fac Biol, Dept Bioquim & Biol Mol, Canc Res Grp, Barcelona 08071, Spain

来源：

DRUG DISCOVERY TODAY | 2008年 / 13卷 / 1-2期

关键词：

D O I：

10.1016/j.drudis.2007.10.008

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cachexia is a complex syndrome. The main components of this pathological state are anorexia and metabolic abnormalities, such as glucose intolerance, fat depletion and muscle protein catabolism among others. The aim of the present article is to review the recent therapeutic approaches that have been designed to fight and counteract muscle wasting in different pathological states such as cancer, AIDS and chronic heart failure.

引用

页码：73 / 78

页数：6

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