Methicillin-resistant Staphylococcus aureus in hospitals in Tbilisi, the Republic of Georgia, are variants of the Brazilian clone

被引：16

作者：

Bartels, M. D. ^{[1
]}

Nanuashvili, A. ^{[2
]}

Boye, K. ^{[1
]}

Rohde, S. M. ^{[1
]}

Jashiashvili, N. ^{[2
]}

Faria, N. A. ^{[3
]}

Kereselidze, M. ^{[4
]}

Kharebava, S. ^{[4
]}

Westh, H. ^{[1
]}

机构：

[1] Hvidovre Univ Hosp, Dept Clin Microbiol, DK-2650 Hvidovre, Denmark

[2] Tbilisi State Med Univ, Tbilisi, Georgia

[3] Univ Nova Lisboa, Inst Tecnol Quim & Biol, Mol Genet Lab, P-2780156 Oeiras, Portugal

[4] Med Ctr CITO, Tbilisi, Georgia

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2008年 / 27卷 / 08期

关键词：

D O I：

10.1007/s10096-008-0500-z

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The purpose of this study was to characterise methicillin-resistant Staphylococcus aureus (MRSA) isolates from the Republic of Georgia, part of the former Soviet Union. Thirty-two non-duplicate MRSA isolates were collected in the period from May 2006 to February 2007. The patient data were analysed and the isolates were characterised by staphylococcal protein A (spa) typing, staphylococcal chromosome cassette mec (SCCmec) typing, multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE) and the detection of Panton-Valentine leukocidin (PVL) genes. Only two closely related spa types were found; 29 isolates were of spa type 459 and three were t030. The spa types belonged to sequence type (ST) 239, clonal complex (CC) 8. All isolates were multiresistant, PVL-negative and harboured SCCmec type IIIA. Based on the molecular findings and PFGE, the isolates most closely resembled the pandemic Brazilian clone (ST239-IIIA).

引用

页码：757 / 760

页数：4

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