Ultra-fast synthesis of magnetic and luminescent silica beads for versatile bioanalytical applications

被引:29
作者
Müller-Schulte, D
Schmitz-Rode, T
Borm, P
机构
[1] MagnaMed GmbH, D-52066 Aachen, Germany
[2] Univ Hosp Aachen, Clin Radiol, Aachen, Germany
[3] Hogesch Zuyd Ctr Expertise Life Sci, NL-6400 Herrlen, Netherlands
关键词
silica; synthesis; DNA separation; encapsulation; quantum dots; photonic crystals; optical codes; inverse sol-gel suspension technique; silica hybrids;
D O I
10.1016/j.jmmm.2005.01.088
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A method for the synthesis of both spherically shaped micro/nano silica particles and silica hybrid particles using a novel inverse sol-gel suspension technique was developed. The technique enables the synthesis of beads within seconds and provides a simple basis for quantum dot and biosubstances encapsulation. The carriers can be used as DNA adsorbents, individually addressable optical codes for bioassays and biomolecule library screening as well as photonic crystals. (c) 2005 Published by Elsevier B.V.
引用
收藏
页码:135 / 143
页数:9
相关论文
共 32 条
[31]  
Yang SM, 2000, ADV MATER, V12, P1940, DOI 10.1002/1521-4095(200012)12:24<1940::AID-ADMA1940>3.0.CO
[32]  
2-D