Analysis of estrogens in water by magnetic octadecylsilane particles extraction and sweeping micellar electrokinetic chromatography

被引：57

作者：

Liu, Yaling

Jia, Li ^{[1
]}

机构：

[1] S China Normal Univ, MOE Key Lab Laser Life Sci, Guangzhou 510631, Guangdong, Peoples R China

[2] S China Normal Univ, Inst Laser Life Sci, Guangzhou 510631, Guangdong, Peoples R China

来源：

MICROCHEMICAL JOURNAL | 2008年 / 89卷 / 01期

基金：

中国国家自然科学基金;

关键词：

sweeping; micellar electrokinetic chromatography; estrogens; magnetic octadecylsilane particles; extraction;

D O I：

10.1016/j.microc.2007.12.003

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A method based on magnetic separation was developed for the extraction of several estrogens (including diethylstilbestrol, estrone and estriol) in water followed by sweeping micellar electrokinetic chromatography (MEKC) analysis with UV detection. Novel magnetic octadecylsilane (ODS) particles were prepared using a silanization method with octadecyl trimethoxysilane as the surface modification reagent of magnetic Fe3O4 particles. Octadecyl trimethoxysilane was covalently immobilized on the magnetic iron oxide particles. The particles were used as the sorbents in the magnetic separation for the extraction of trace amounts of estrogens from water. The extraction condition and efficiency of the particles for the estrogens were investigated. Combining the magnetic ODS particles extraction and sweeping MEKC with UV detection, the estrogens at concentrations as low as ng/mL in water can be detected without interference from other substances in the sample matrix. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：72 / 76

页数：5

共 22 条

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