Uncovering RNAi mechanisms in plants: Biochemistry enters the foray

被引：40

作者：

Qi, YJ ^{[1
]}

Hannon, GJ ^{[1
]}

机构：

[1] Cold Spring Harbor Lab, Watson Sch Biol Sci, Cold Spring Harbor, NY 11724 USA

来源：

FEBS LETTERS | 2005年 / 579卷 / 26期

关键词：

RNA interference; dicer-like protein; argonaute; RNA-induced silencing complex; biochemistry;

D O I：

10.1016/j.febslet.2005.08.035

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In plants, the RNA interference (RNAi) machinery responds to a variety of triggers including viral infection, transgenes, repeated elements and transposons. All of these triggers lead to silencing outcomes ranging from mRNA degradation to translational repression to chromatin remodeling. Thus, plants offer us a potentially unique opportunity to understand the full range of RNAi effector mechanisms. In this review, we discuss the recent developments in our understanding of plant RNAi mechanisms from a biochemical perspective. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：5899 / 5903

页数：5

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