Pathogenicity islands and virulence evolution in Listeria

被引:173
作者
Vázquez-Boland, JA
Domínguez-Bernal, G
González-Zorn, B
Kreft, J
Goebel, W
机构
[1] Univ Complutense Madrid, Fac Vet, Grp Patogenesis Mol Bacteriana, Unidad Microbiol & Inmunol,Dept Patol Anim 1, E-28040 Madrid, Spain
[2] Univ Wurzburg, Lehrstuhl Mikrobiol, Biozentrum, D-97074 Wurzburg, Germany
关键词
Listeria; Listeria monocytogenes; Listeria innocua; Listeria ivanovii; pathogenicity islands; LIPI-1; LIPI-2; LRR proteins; virulence evolution; microbial pathogenesis;
D O I
10.1016/S1286-4579(01)01413-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
As in other bacterial pathogens, the virulence determinants of Listeria species are clustered in genomic islands scattered along the chromosome. This review summarizes current knowledge about the structure, distribution and role in pathogenesis of Listeria virulence loci. Hypotheses about the mode of acquisition and evolution of these loci in this group of Gram-positive bacteria are presented and discussed. (C) 2001 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:571 / 584
页数:14
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