Polyelectrolytes for cell encapsulation

被引：114

作者：

Bhatia, SR ^{[1
]}

Khattak, SF ^{[1
]}

Roberts, SC ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Chem Engn, Goessmann Lab 159, Amherst, MA 01003 USA

来源：

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE | 2005年 / 10卷 / 1-2期

关键词：

alginate; tissue engineering; polyelectrolyte complexes; polyelectrolyte gels; immunoprotective membranes;

D O I：

10.1016/j.cocis.2005.05.004

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Recent advances in the use of polyelectrolyte materials for cell encapsulation are reviewed, with a focus on three current challenges: tunable mechanical properties, controlled cell adhesion, and enhanced oxygen supply. New notable results include methods for creating stable alginate-silica complexes, techniques for incorporating RGD-containing peptides into alginate gels, and an improved understanding of the effect of charge density on cell-material interactions. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：45 / 51

页数：7

共 56 条

[1] Stability assessment of chitosan-sodium hexametaphosphate capsules [J].

Angelova, N ;

Hunkeler, D .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2001, 12 (11) :1207-1225

[2] Internal support of tissue-engineered cartilage [J].

Arévalo-Silva, CA ;

Eavey, RD ;

Cao, YL ;

Vacanti, M ;

Weng, YL ;

Vacanti, CA .

ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2000, 126 (12) :1448-1452

[3] Carrageenan-oligochitosan microcapsules: optimization of the formation process [J].

Bartkowiak, A ;

Hunkeler, D .

COLLOIDS AND SURFACES B-BIOINTERFACES, 2001, 21 (04) :285-298

[4]

BERTHIAUME F, 2000, TISSUE ENG BIOMEDICA, V2

[5] Improving cell encapsulation through size control [J].

Canaple, L ;

Rehor, A ;

Hunkeler, D .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2002, 13 (07) :783-796

[6]

Cao YL, 1998, J BIOMAT SCI-POLYM E, V9, P475

[7] Evaluation of modified alginate-chitosan-polyethylene glycol microcapsules for cell encapsulation [J].

Chandy, T ;

Mooradian, DL ;

Rao, GHR .

ARTIFICIAL ORGANS, 1999, 23 (10) :894-903

[8] Multi-layered microcapsules for cell encapsulation [J].

Chia, SM ;

Wan, ACA ;

Quek, CH ;

Mao, HQ ;

Xu, X ;

Shen, L ;

Ng, ML ;

Leong, KW ;

Yu, H .

BIOMATERIALS, 2002, 23 (03) :849-856

[9] Engineering challenges in cell-encapsulation technology [J].

Colton, CK .

TRENDS IN BIOTECHNOLOGY, 1996, 14 (05) :158-162

[10] IMPLANTABLE BIOHYBRID ARTIFICIAL ORGANS [J].

COLTON, CK .

CELL TRANSPLANTATION, 1995, 4 (04) :415-436

← 1 2 3 4 5 6 →