Activity Profile Sequences: a Concept to Account for the Progression of Compound Activity in Target Space and to Extract SAR Information from Analogue Series with Multiple Target Annotations

被引：1

作者：

Hu, Ye ^{[1
]}

Bajorath, Juergen ^{[1
]}

机构：

[1] Rhein Freidrich Wilhelms Univ Bonn, Dept Life Sci Informat, B IT LIMES Program, Unit Chem Biol & Med Chem, D-53113 Bonn, Germany

来源：

CHEMMEDCHEM | 2011年 / 6卷 / 12期

关键词：

activity profiles; polypharmacology; profile sequences; scaffolds; structure-activity relationships; target annotations;

D O I：

10.1002/cmdc.201100395

中图分类号：

R914 [药物化学];

学科分类号：

100705 [微生物与生化药学];

摘要：

[No abstract available]

引用

页码：2150 / 2154

页数：5

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