Potential of a simplified p24 assay for early diagnosis of infant human immunodeficiency virus type 1 infection in Haiti

被引：22

作者：

George, Erik

Beauharnais, Carole Anne

Brignoli, Emilio

Noel, Francine

Bois, Gyrlande

Rouzier, Patricia De Matteis

Altenor, Martine

Lauture, Daniel

Hosty, Marlene

Mehta, Sapna

Wright, Peter F.

Pape, Jean W.

机构：

[1] Cornell Univ, Dept Med, Div Int Med & Infect Dis, Weill Med Coll, New York, NY USA

[2] GHESIKO, Port Au Prince, Haiti

[3] Hop Immaculee Concept Cayes, Les Cayes, Haiti

[4] Vanderbilt Univ, Sch Med, Dept Pediat, Div Pediat Infect Dis, Nashville, TN 37212 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2007年 / 45卷 / 10期

关键词：

D O I：

10.1128/JCM.01314-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

With global efforts to scale up the prevention of mother-to-child transmission services and pediatric antiretrovirall therapy, there is an urgent need to introduce a simple, low-cost infant human immunodeficiency virus test in the field. We postulated that the p24 antigen capture enzyme-linked immunosorbent assay could be simplified by eliminating signal amplification without compromising diagnostic accuracy.

引用

收藏

页码：3416 / 3418

页数：3

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