And the Best Picture is - the HIV gp120 envelope, please!

被引:6
作者
Berger, EA [1 ]
机构
[1] NIAID, Viral Dis Lab, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/1362
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
X-ray crystallographic structure of the gp 120 core coupled with mutagenesis analyses reveal details of receptor interactions and multiple layers of immune evasion.
引用
收藏
页码:671 / 674
页数:4
相关论文
共 11 条
  • [1] Analysis of the interaction of antibodies with a conserved, enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120
    Binley, JM
    Wyatt, R
    Desjardins, E
    Kwong, PD
    Hendrickson, W
    Moore, JP
    Sodroski, J
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 1998, 14 (03) : 191 - 198
  • [2] Core structure of gp41 from the HIV envelope glycoprotein
    Chan, DC
    Fass, D
    Berger, JM
    Kim, PS
    [J]. CELL, 1997, 89 (02) : 263 - 273
  • [3] Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
    Kwong, PD
    Wyatt, R
    Robinson, J
    Sweet, RW
    Sodroski, J
    Hendrickson, WA
    [J]. NATURE, 1998, 393 (6686) : 648 - 659
  • [4] A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding
    Rizzuto, CD
    Wyatt, R
    Hernández-Ramos, N
    Sun, Y
    Kwong, PD
    Hendrickson, WA
    Sodroski, J
    [J]. SCIENCE, 1998, 280 (5371) : 1949 - 1953
  • [5] CRYSTAL-STRUCTURE OF AN HIV-BINDING RECOMBINANT FRAGMENT OF HUMAN CD4
    RYU, SE
    KWONG, PD
    TRUNEH, A
    PORTER, TG
    ARTHOS, J
    ROSENBERG, M
    DAI, XP
    XUONG, NH
    AXEL, R
    SWEET, RW
    HENDRICKSON, WA
    [J]. NATURE, 1990, 348 (6300) : 419 - 426
  • [6] CHARACTERIZATION OF CONSERVED HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 GP120 NEUTRALIZATION EPITOPES EXPOSED UPON GP120-CD4 BINDING
    THALI, M
    MOORE, JP
    FURMAN, C
    CHARLES, M
    HO, DD
    ROBINSON, J
    SODROSKI, J
    [J]. JOURNAL OF VIROLOGY, 1993, 67 (07) : 3978 - 3988
  • [7] ATOMIC-STRUCTURE OF A FRAGMENT OF HUMAN CD4 CONTAINING 2 IMMUNOGLOBULIN-LIKE DOMAINS
    WANG, JH
    YAN, YW
    GARRETT, TPJ
    LIU, JH
    RODGERS, DW
    GARLICK, RL
    TARR, GE
    HUSAIN, Y
    REINHERZ, EL
    HARRISON, SC
    [J]. NATURE, 1990, 348 (6300) : 411 - 418
  • [8] Atomic structure of the ectodomain from HIV-1 gp41
    Weissenhorn, W
    Dessen, A
    Harrison, SC
    Skehel, JJ
    Wiley, DC
    [J]. NATURE, 1997, 387 (6631) : 426 - 430
  • [9] Dimeric association and segmental variability in the structure of human CD4
    Wu, H
    Kwong, PD
    Hendrickson, WA
    [J]. NATURE, 1997, 387 (6632) : 527 - 530
  • [10] The antigenic structure of the HIV gp120 envelope glycoprotein
    Wyatt, R
    Kwong, PD
    Desjardins, E
    Sweet, RW
    Robinson, J
    Hendrickson, WA
    Sodroski, JG
    [J]. NATURE, 1998, 393 (6686) : 705 - 711