An unusual ring expansion from the Zav'yalov pyrrole synthesis:: formation of oxacino[2,3-c]pyrroles

被引：10

作者：

Gabbutt, CD

Hepworth, JD

Heron, BM ^{[1
]}

Elsegood, MRJ

Clegg, W

机构：

[1] Univ Hull, Dept Chem, Hull HU6 7RX, N Humberside, England

[2] Univ Newcastle Upon Tyne, Dept Chem, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 03期

关键词：

D O I：

10.1039/a809033e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enamino acids 2 and 5 undergo a facile cyclisation to afford the pyrrole 3 and isoindole 6 ring systems; a novel two atom ring expansion ensues when derivatives 5b,d are subjected to the cyclisation conditions, resulting in the formation of the new oxacino[2,3-c]pyrrole system, the structure of which is confirmed by X-ray crystallography.

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收藏

页码：289 / 290

页数：2

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