Synthesis and antimycobacterial activity of capuramycin analogues. Part 2: Acylated derivatives of capuramycin-related compounds

被引：34

作者：

Hotoda, H

Daigo, M

Furukawa, M

Murayama, K

Hasegawa, CA

Kaneko, M

Muramatsu, Y

Ishii, MM

Miyakoshi, S

Takatsu, T

Inukai, M

Kakuta, M

Abe, T

Fukuoka, T

Utsui, Y

Ohya, S

机构：

[1] Sankyo Co Ltd, New Drug Dev Div, Drug Safety Dept,Exploratory Chem Res Labs, Shinagawa Ku, Tokyo 1408710, Japan

[2] Sankyo Co Ltd, Biomed Res Labs, Shinagawa Ku, Tokyo 1408710, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 17期

关键词：

D O I：

10.1016/S0960-894X(03)00597-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Acylated derivatives of capuramycin and A-500359A were synthesized and tested for antimycobacterial activity. Compound 20 having a decanoyl group showed very potent activity. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：2833 / 2836

页数：4

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