Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish Diabetes Prevention Study

被引：148

作者：

Ilanne-Parikka, Pirjo ^{[1
,2
]}

Eriksson, Johan G. ^{[3
,4
]}

Lindstrom, Jaana ^{[3
]}

Peltonen, Markku ^{[3
]}

Aunola, Sirkka ^{[5
]}

Hamalainen, Helena ^{[6
]}

Keinanen-Kiukaanniemi, Sirkka ^{[7
,8
,9
]}

Laakso, Mauri ^{[7
,8
,10
]}

Valle, Timo T. ^{[3
]}

Lahtela, Jorma ^{[11
]}

Uusitupa, Matti ^{[12
]}

Tuomilehto, Jaakko ^{[3
,4
]}

机构：

[1] Finnish Diabet Associat, Ctr Diabet, Tampere, Finland

[2] Pirkanmaa Hosp Dist, Dept Res Adm, Tampere, Finland

[3] Natl Publ Hlth Inst, Diabet Unit, Dept Hlth Promot & Chron Dis Prevent, Helsinki, Finland

[4] Univ Helsinki, Dept Publ Hlth, Helsinki, Finland

[5] Natl Inst Publ Hlth, Lab Populat Res, Dept Hlth & Funct Capac, Turku, Finland

[6] Social Insurance Inst, Res Dept, Turku, Finland

[7] Univ Oulu, Dept Publ Hlth Sci & Gen Practice, Oulu, Finland

[8] Oulu Deaconess Inst, Dept Sport Med, Oulu, Finland

[9] Oulu Hlth Ctr, Oulu, Finland

[10] Oulu Univ Hosp, Unit Gen Practice, Oulu, Finland

[11] Tampere Univ Hosp, Dept Internal Med, Tampere, Finland

[12] Univ Kuopio, Dept Publ Hlth & Clin Nutr, FIN-70211 Kuopio, Finland

来源：

DIABETES CARE | 2008年 / 31卷 / 04期

关键词：

D O I：

10.2337/dc07-1117

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE - The aim of this secondary analysis of the Finnish Diabetes Prevention Study was to assess the effects of lifestyle intervention on metabolic syndrome and its components. RESEARCH DESIGN AND METHODS - A total of 522 middle-aged overweight men and women with impaired glucose tolerance were randomized into an individualized lifestyle intervention group or a standard care control group. National Cholesterol Education Program criteria were used for the definition of metabolic syndrome. RESULTS - At the end of the study, with a mean follow-up of 3.9 years, we found a significant reduction in the prevalence of metabolic syndrome in the intervention group compared with the control group (odds ratio [OR] 0.62 [95% CI 0.40-0.95]) and in the prevalence of abdominal obesity (0.48 [0.28-0.81]). CONCLUSIONS - The results suggest that lifestyle intervention may also reduce risk of cardiovascular disease in the long run.

引用

页码：805 / 807

页数：3

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