Motor fluctuations and dyskinesia in Parkinson's disease

被引：90

作者：

Nutt, JG ^{[1
]}

机构：

[1] Oregon Hlth Sci Univ, Sch Med, Dept Neurol, Portland, OR 97201 USA

[2] Oregon Hlth Sci Univ, Sch Med, Dept Physiol & Pharmacol, Portland, OR 97201 USA

来源：

PARKINSONISM & RELATED DISORDERS | 2001年 / 8卷 / 02期

关键词：

Parkinson's disease; levodopa; motor fluctuations; levodopa-induced dyskinesia;

D O I：

10.1016/S1353-8020(01)00024-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Motor fluctuations and dyskinesia are common complications of long-term levodopa therapy. The neural and molecular mechanisms underlying their development are partially understood. A variety of clinical strategies may reduce the unpredictability of motor fluctuations and reduce their impact. Prevention of these complications remains an elusive goal. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：101 / 108

页数：8

共 71 条

[1]

Ahlskog JE, 1996, MAYO CLIN PROC, V71, P659

[2] EFFECT OF ANTICHOLINERGIC DRUGS ON GASTROINTESTINAL ABSORPTION OF L-DOPA IN RATS AND IN MAN [J].

ALGERI, S ;

CERLETTI, C ;

CURCIO, M ;

MORSELLI, PL ;

BONOLLO, L ;

BUNIVA, G ;

MINAZZI, M ;

MINOLI, G .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1976, 35 (02) :293-299

[3]

[Anonymous], PARKINSONS DIS CURRE

[4]

Barbeau A, 1974, Adv Neurol, V5, P347

[5]

Barbeau A., 1980, Parkinson's disease: current progress, problems and management

[6]

proceedings, P229

[7] INFLUENCE OF MEAL INGESTION TIME ON PHARMACOKINETICS OF ORALLY-ADMINISTERED LEVODOPA IN PARKINSONIAN-PATIENTS [J].

BARUZZI, A ;

CONTIN, M ;

RIVA, R ;

PROCACCIANTI, G ;

ALBANI, F ;

TONELLO, C ;

ZONI, E ;

MARTINELLI, P .

CLINICAL NEUROPHARMACOLOGY, 1987, 10 (06) :527-537

[8] Comparison of immediate-release and controlled release carbidopa/levodopa in Parkinson's disease - A multicenter 5-year study [J].

Block, G ;

Liss, C ;

Reines, S ;

Irr, J ;

Nibbelink, D ;

Aarli, J ;

Aguilar, M ;

Ahrens, S ;

Bakheit, A ;

Baumel, B ;

Bertoni, J ;

Capildeo, R ;

CastroCaldas, A ;

Deza, L ;

Donaldson, I ;

Franck, G ;

Fusillo, J ;

Gauthier, S ;

Gershanik, O ;

Granerus, AK ;

Hauser, RA ;

Hennessey, K ;

Hutton, JT ;

Joffe, R ;

Koller, W ;

Last, B ;

LeWitt, P ;

Mamoli, B ;

Manyam, B ;

Mark, M ;

Nakano, K ;

Nausieda, P ;

Otero, E ;

Paulson, G ;

Pinter, M ;

Reich, S ;

Rodnitzky, R ;

Sage, J ;

Sampaio, C ;

Smith, B ;

Teravainen, H ;

Tetrud, J ;

Tolosa, E ;

Ulm, G ;

Valesco, F .

EUROPEAN NEUROLOGY, 1997, 37 (01) :23-27

[9] BUSPIRONE IN LEVODOPA-INDUCED DYSKINESIAS [J].

BONIFATI, V ;

FABRIZIO, E ;

CIPRIANI, R ;

VANACORE, N ;

MECO, G .

CLINICAL NEUROPHARMACOLOGY, 1994, 17 (01) :73-82

[10] SINEMET-FERROUS SULFATE INTERACTION IN PATIENTS WITH PARKINSONS-DISEASE [J].

CAMPBELL, NRC ;

RANKINE, D ;

GOODRIDGE, AE ;

HASINOFF, BB ;

KARA, M .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1990, 30 (04) :599-605

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