Enhancement of the antitumour activity for the synthesised dodecylcysteine surfactant using gold nanoparticles

被引:15
作者
Azzam, E. M. S. [1 ]
Morsy, S. M. I. [1 ]
机构
[1] Egyptian Petr Res Inst, Appl Surfactant Lab, Petrochem Dept, Cairo 11727, Egypt
关键词
dodecylcysteine hydrochloride surfactant; gold nanoparticles; surface properties; antitumour activity;
D O I
10.1007/s11743-008-1072-8
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
In this paper, the surfactant dodecylcysteine hydrochloride was synthesised. The surface parameters of the synthesised surfactant were studied using a surface tension technique. The surface parameters show a good surface activity of the prepared surfactant in aqueous solution. The self-assembling behaviour of the synthesised surfactant comparing with that of cysteine compound on the prepared gold nanoparticles was confirmed using transmission electron microscope (TEM) measurements. The effect of self-assembling of this surfactant on the size of gold nanoparticles was studied using TEM images. The antitumour activity of the prepared surfactant without and with the gold nanoparticles was investigated. The results show that the antitumour activity of the prepared surfactant was enhanced with the presences of the gold nanoparticles.
引用
收藏
页码:195 / 199
页数:5
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