Human rhinovirus C-Associated severe pneumonia in a neonate

被引：31

作者：

Broberg, Eeva ^{[1
]}

Niemela, Jussi ^{[2
]}

Lahti, Elina ^{[2
]}

Hyypia, Timo ^{[1
]}

Ruuskanen, Olli ^{[2
]}

Waris, Matti ^{[1
]}

机构：

[1] Univ Turku, Dept Virol, FI-20520 Turku, Finland

[2] Turku Univ Hosp, Dept Pediat, FI-20520 Turku, Finland

来源：

JOURNAL OF CLINICAL VIROLOGY | 2011年 / 51卷 / 01期

关键词：

Rhinovirus; Respiratory; Infection; Pneumonia; Neonatal; CHILDREN; INFECTIONS; SURVEILLANCE; STRAINS;

D O I：

10.1016/j.jcv.2011.01.018

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We present a case of severe pneumonia, associated with a prolonged infection by a species C rhinovirus (HRV) in a 3-week old neonate. HRV RNA was identified in nasal and nasopharyngeal secretions, bronchoalveolar lavage and bronchial specimens, stool and urine, collected from the patient during a one-month period. No other viral or bacterial agents were detected. Sequence analysis of two regions of the viral genome, amplified directly from the clinical specimens revealed a novel HRV-C variant. These observations highlight the occurrence of severe neonatal infections caused by HRVs and the need of rapid viral diagnostics for their detection. (C) 2011 Elsevier B. V. All rights reserved.

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页码：79 / 82

页数：4

相关论文

共 23 条

[1] Molecular characterization of human rhinovirus field strains isolated during surveillance of enteroviruses [J].

Blomqvist, Soile ;

Savolainen-Kopra, Carita ;

Paananen, Anja ;

Hovi, Tapani ;

Roivainen, Merja .

JOURNAL OF GENERAL VIROLOGY, 2009, 90 :1371-1381

[2] Role of Rhinovirus C in Apparently Life-Threatening Events in Infants, Spain [J].

Calvo, Cristina ;

Luz Garcia, M. ;

Pozo, Francisco ;

Reyes, Noelia ;

Perez-Brena, Pilar ;

Casas, Inmaculada .

EMERGING INFECTIOUS DISEASES, 2009, 15 (09) :1506-1508

[3] Viruses in community-acquired pneumonia in children aged less than 3 years old: High rate of viral coinfection [J].

Cilla, Gustavo ;

Onate, Eider ;

Perez-Yarza, Eduardo G. ;

Montes, Milagrosa ;

Vicente, Diego ;

Perez-Trallero, Emilio .

JOURNAL OF MEDICAL VIROLOGY, 2008, 80 (10) :1843-1849

[4] The cis-acting replication elements define human enterovirus and rhinovirus species [J].

Cordey, Samuel ;

Gerlach, Daniel ;

Junier, Thomas ;

Zdobnov, Evgeny M. ;

Kaiser, Laurent ;

Tapparel, Caroline .

RNA, 2008, 14 (08) :1568-1578

[5]

Hyypiä T, 1998, J CLIN MICROBIOL, V36, P2081

[6] Etiology of community-acquired pneumonia in 254 hospitalized children [J].

Juvén, T ;

Mertsola, J ;

Waris, M ;

Leinonen, M ;

Meurman, O ;

Roivainen, M ;

Eskola, J ;

Saikku, P ;

Ruuskanen, O .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2000, 19 (04) :293-298

[7] Recurrent and persistent respiratory tract viral infections in patients with primary hypogammaglobulinemia [J].

Kainulainen, Leena ;

Vuorinen, Tytti ;

Rantakokko-Jalava, Kaisu ;

Osterback, Riikka ;

Ruuskanen, Olli .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (01) :120-126

[8] Chronic rhinoviral infection in lung transplant recipients [J].

Kaiser, Laurent ;

Aubert, John-David ;

Pache, Jean-Claude ;

Deffernez, Christelle ;

Rochat, Thierry ;

Garbino, Jorge ;

Wunderli, Werner ;

Meylan, Pascal ;

Yerly, Sabine ;

Perrin, Luc ;

Letovanec, Igor ;

Nicod, Laurent ;

Tapparel, Caroline ;

Soccal, Paola M. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 174 (12) :1392-1399

[9] RHINOVIRUS ASSOCIATED WITH SEVERE LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN [J].

Louie, Janice K. ;

Roy-Burman, Arup ;

Guardia-LaBar, Lilly ;

Boston, Erica J. ;

Kiang, David ;

Padilla, Tasha ;

Yagi, Shigeo ;

Messenger, Sharon ;

Petru, Ann M. ;

Glaser, Carol A. ;

Schnurr, David P. .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2009, 28 (04) :337-339

[10] Human rhinoviruses: The cold wars resume [J].

Mackay, Ian M. .

JOURNAL OF CLINICAL VIROLOGY, 2008, 42 (04) :297-320