The effect of DMSO on the borohydride reduction of a cyclohexanone: A formal enantioselective synthesis of (+)-epibatidine.

被引：33

作者：

Barros, MT ^{[1
]}

Maycock, CD

Ventura, MR

机构：

[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Quim, P-2825 Monte De Caparica, Portugal

[2] Univ Nova Lisboa, Inst Tecnol Quim & Biol, P-2780 Oeiras, Portugal

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 03期

关键词：

D O I：

10.1016/S0040-4039(98)02354-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An asymmetric synthesis of (+)-epibatidine is described which uses the increased stereoselectivity of a borohydride reduction induced by the presence of DMSO. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：557 / 560

页数：4

共 24 条

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