Line scan diffusion tensor MRI of the cervical spinal cord in preterm infants

被引：45

作者：

Murphy, BP ^{[1
]}

Zientara, GP ^{[1
]}

Huppi, PS ^{[1
]}

Maier, SE ^{[1
]}

Barnes, PD ^{[1
]}

Jolesz, FA ^{[1
]}

Volpe, JJ ^{[1
]}

机构：

[1] Brigham & Womens Hosp, Div Newborn Med, Boston, MA 02115 USA

来源：

JOURNAL OF MAGNETIC RESONANCE IMAGING | 2001年 / 13卷 / 06期

关键词：

diffusion tensor; spinal cord; human neonate; MRI; development;

D O I：

10.1002/jmri.1136

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];

摘要：

Line scan diffusion tensor magenetic resonance imaging (DT-MRI) of the cervical spinal cord was demonstrated In vivo for unsedated preterm (gestational age 24-30 weeks at birth), very low birthweight (birthweight 620-1300 g) Infants at postmenstrual ages from 29-40 weeks. Scalar Invariant measures of diffusion [apparent diffusion coefficient (ADC) and relative anisotropy (RA)] determined from a cervical cord region of Interest in each case are reported, characterizing the maturational status of the normal third trimester and newborn spinal cord. Mean ADC of 11 infants was 1.2 +/- 0.1 mum(2)/msec and the mean RA was 24.3 +/- 4.9%. Normal infant cord neural fiber tract morphology was visualized using a mapping of the predominant diffusion tensor eigenvector. Potential clinical applications of line scan DT-MRI of the spinal cord of preterm and term newborns for assessment of spinal cord injury are discussed. J. Magn. Reson. Imaging 2001;13:949-953. (C) 2001 Wiley-Liss, Inc.

引用

页码：949 / 953

页数：5

共 26 条

[1]

A simplified method to measure the diffusion tensor from seven MR images [J].

Basser, PJ ;

Pierpaoli, C .

MAGNETIC RESONANCE IN MEDICINE, 1998, 39 (06) :928-934

[2]

MR DIFFUSION TENSOR SPECTROSCOPY AND IMAGING [J].

BASSER, PJ ;

MATTIELLO, J ;

LEBIHAN, D .

BIOPHYSICAL JOURNAL, 1994, 66 (01) :259-267

[3]

Basser PJ, 1996, J MAGN RESON SER B, V111, P209, DOI [10.1006/jmrb.1996.0086, 10.1016/j.jmr.2011.09.022]

[4]

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury - Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial [J].

Bracken, MB ;

Shepard, MJ ;

Holford, TR ;

LeoSummers, L ;

Aldrich, EF ;

Fazl, M ;

Fehlings, M ;

Herr, DL ;

Hitchon, PW ;

Marshall, LF ;

Nockels, RP ;

Pascale, V ;

Perot, PL ;

Piepmeier, J ;

Sonntag, VKH ;

Wagner, F ;

Wilberger, JE ;

Winn, HR ;

Young, W .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (20) :1597-1604

[5]

Clark CA, 1999, MAGN RESON MED, V41, P1269, DOI 10.1002/(SICI)1522-2594(199906)41:6<1269::AID-MRM26>3.0.CO

[6]

2-2

[7]

Finsterbusch J, 1999, MAGNET RESON MED, V42, P772, DOI 10.1002/(SICI)1522-2594(199910)42:4<772::AID-MRM20>3.0.CO

[8]

2-8

[9]

MRI CHARACTERIZATION OF DIFFUSION-COEFFICIENTS IN A RAT SPINAL-CORD INJURY MODEL [J].

FORD, JC ;

HACKNEY, DB ;

ALSOP, DC ;

JARA, H ;

JOSEPH, PM ;

HAND, CM ;

BLACK, P .

MAGNETIC RESONANCE IN MEDICINE, 1994, 31 (05) :488-494

[10]

Line scan diffusion imaging [J].

Gudbjartsson, H ;

Maier, SE ;

Mulkern, RV ;

Morocz, IA ;

Patz, S ;

Jolesz, FA .

MAGNETIC RESONANCE IN MEDICINE, 1996, 36 (04) :509-519

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