Bonded cellulose-derived high-performance liquid chromatography chiral stationary phases .1. Influence of the degree of fixation on selectivity

被引：90

作者：

Minguillon, C ^{[1
]}

Franco, P ^{[1
]}

Oliveros, L ^{[1
]}

Lopez, P ^{[1
]}

机构：

[1] CONSERVATOIRE NATL ARTS & METIERS,LAB CHIM GEN,F-75141 PARIS 03,FRANCE

来源：

JOURNAL OF CHROMATOGRAPHY A | 1996年 / 728卷 / 1-2期

关键词：

chiral stationary phases; LC; cellulose-derived stationary phases; enantiomer separation; enantioselectivity; beta-blockers; lorazepam; naproxen; warfarin;

D O I：

10.1016/0021-9673(95)01123-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Four mixed 10-undecenoyl-3,5-dimethylphenylaminocarbonyl derivatives of cellulose, with an increasing proportion of alkenoyl groups, were synthesized and chemically bonded on allylsilica gel. The influence of the degree of fixation of the cellulose derivative on the matrix for the four resulting chiral stationary phases on their selectivity is discussed.

引用

页码：407 / 414

页数：8

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