Antibodies in the breakdown lane

被引：4

作者：

Blumberg, RS

Lencer, WI

机构：

[1] Brigham & Womens Hosp, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA 02115 USA

[3] Childrens Hosp, Med Ctr, Boston, MA 02115 USA

来源：

NATURE BIOTECHNOLOGY | 2005年 / 23卷 / 10期

关键词：

D O I：

10.1038/nbt1005-1232

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

[No abstract available]

引用

收藏

页码：1232 / 1234

页数：4

相关论文

共 13 条

[1]

The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease [J].

Akilesh, S ;

Petkova, S ;

Sproule, TJ ;

Shaffer, DJ ;

Christianson, GJ ;

Roopenian, D .

JOURNAL OF CLINICAL INVESTIGATION, 2004, 113 (09) :1328-1333

[2]

Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway [J].

Bitonti, AJ ;

Dumont, JA ;

Low, SC ;

Peters, RT ;

Kropp, KE ;

Palombella, VJ ;

Stattel, JM ;

Lu, YC ;

Tan, CA ;

Song, JJ ;

Garcia, AM ;

Simister, NE ;

Spiekermann, GM ;

Lencer, WI ;

Blumberg, RS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (26) :9763-9768

[3]

Increasing the affinity of a human IgG1, for the neonatal Fc receptor: Biological consequences [J].

Dall'Acqua, WF ;

Woods, RM ;

Ward, ES ;

Palaszynski, SR ;

Patel, NK ;

Brewah, YA ;

Wu, H ;

Kiener, PA ;

Langermann, S .

JOURNAL OF IMMUNOLOGY, 2002, 169 (09) :5171-5180

[4]

Pharmacokinetic effects of 4C9, an anti-FcRn antibody, in rats: implications for the use of FcRn inhibitors for the treatment of humoral autoimmune and alloimmune conditions [J].

Getman, KE ;

Balthasar, JP .

JOURNAL OF PHARMACEUTICAL SCIENCES, 2005, 94 (04) :718-729

[5]

Increasing the serum persistence of an IgG fragment by random mutagenesis [J].

Ghetie, V ;

Popov, S ;

Borvak, J ;

Radu, C ;

Matesoi, D ;

Medesan, C ;

Ober, RJ ;

Ward, ES .

NATURE BIOTECHNOLOGY, 1997, 15 (07) :637-640

[6]

Engineered human IgG antibodies with longer serum half-lives in primates [J].

Hinton, PR ;

Johlfs, MG ;

Xiong, JM ;

Hanestad, K ;

Ong, KC ;

Bullock, C ;

Keller, S ;

Tang, MT ;

Tso, JY ;

V squez, M ;

Tsurushita, N .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (08) :6213-6216

[7]

Mechanisms of intravenous immunoglobulin action in immune thrombocytopenic purpura [J].

Jin, F ;

Balthasar, JP .

HUMAN IMMUNOLOGY, 2005, 66 (04) :403-410

[8]

Finally! The Brambell receptor (FcRB) - Mediator of transmission of immunity and protection from catabolism for IgG [J].

Junghans, RP .

IMMUNOLOGIC RESEARCH, 1997, 16 (01) :29-57

[9]

beta(2)-microglobulin-deficient mice are resistant to bullous pemphigoid [J].

Liu, Z ;

Roopenian, DC ;

Zhou, XO ;

Christianson, GJ ;

Diaz, LA ;

Sedmak, DD ;

Anderson, CL .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (05) :777-783

[10]

Crystal structure at 2.8 Å of an FcRn/heterodimeric Fc complex:: Mechanism of pH-dependent binding [J].

Martin, WL ;

West, AP ;

Gan, L ;

Bjorkman, PJ .

MOLECULAR CELL, 2001, 7 (04) :867-877