The secretome of the maize pathogen Ustilago maydis

被引:147
作者
Mueller, Olaf [1 ]
Kahmann, Regine [1 ]
Aguilar, Guillermo [2 ]
Trejo-Aguilar, Blanca [2 ]
Wu, Andy [2 ]
de Vries, Ronald P. [2 ]
机构
[1] Max Planck Inst Terr Microbiol, D-35043 Marburg, Germany
[2] Univ Utrecht, Dept Biol, NL-3584 CH Utrecht, Netherlands
关键词
secreted proteins; genome; Ustilago maydis; maize pathogen;
D O I
10.1016/j.fgb.2008.03.012
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Ustilago maydis establishes a biotrophic relationship with its host plant, i.e. plant cells stay alive despite massive fungal growth in infected tissue. The genome sequence has revealed that U. maydis is poorly equipped with plant cell wall degrading enzymes and uses novel secreted protein effectors as crucial determinants for biotrophic development. Many of these effector genes are clustered and differentially regulated during plant colonization. In this review, we analyze the secretome of U. maydis by differentiating between secreted enzymes, likely structural proteins of the fungal cell wall (excluding GPI-anchored proteins) as well as likely effectors with either apoplastic or cytoplasmic function. This classification is based on the presence of functional domains, general domain structure and cysteine pattern. In addition, we discuss possible functions of selected protein classes with a special focus on disease development. (C) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:S63 / S70
页数:8
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