Direct palladium/copper oxidative cross-coupling of α-methylstyrene with acrylates

被引：7

作者：

Al-Maksoud, Walid ^{[1
]}

Djakovitch, Laurent ^{[1
]}

Jahjah, Mohamad ^{[1
]}

Pinel, Catherine ^{[1
]}

机构：

[1] Univ Lyon, Inst Rech Catalyse & Environm Lyon, CNRS, UMR 5256, F-69626 Villeurbanne, France

来源：

SCIENCE CHINA-CHEMISTRY | 2010年 / 53卷 / 09期

关键词：

direct cross-coupling; oxidative couplings; palladium; copper; catalytic procedures; olefin cross-coupling; FREE NH-INDOLES; C3-ALKENYLATION; CATALYST;

D O I：

10.1007/s11426-010-4096-7

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fully palladium/copper catalytic oxidative cross-coupling of acrylates with alpha-methylstyrene was performed in a DMSO/AcOH (1:1) mixture at 60 A degrees C in the air. This improves previous procedures which employed stoichiometric amounts of copper and oxygen. Thus various acrylates were effectively coupled to alpha-methylstyrene giving the expected compounds in moderate to good yields (44%-65%) as a mixture of E and Z isomers.

引用

页码：1927 / 1931

页数：5

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