Cell apoptosis induced by carcinogenic metals

被引：102

作者：

Chen, F ^{[1
]}

Vallyathan, V ^{[1
]}

Castranova, V ^{[1
]}

Shi, L ^{[1
]}

机构：

[1] NIOSH, Hlth Effects Lab Div, Morgantown, WV 26505 USA

来源：

MOLECULAR AND CELLULAR BIOCHEMISTRY | 2001年 / 222卷 / 1-2期

关键词：

apoptosis; metal; ROS; DNA damage; carcinogenesis;

D O I：

10.1023/A:1017970330982

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Well-documented evidence suggests that environmental and occupational exposure of toxic metals or metal-containing compounds can cause a number of human diseases, including inflammation and cancer, through DNA damage, protein modifications, or lipid peroxidation. This mini-review addresses the mechanisms of cell death induced by some carcinogenic metals, including arsenic (III), chromium (VI) and vanadium (V). A possible contribution of reactive oxygen species to metal-induced cell death is also discussed.

引用

页码：183 / 188

页数：6

共 56 条

[11]

Buzard Gregory S., 2000, Journal of Environmental Pathology Toxicology and Oncology, V19, P179

[12] Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia [J].

Cai, X ;

Shen, YL ;

Zhu, Q ;

Jia, PM ;

Yu, Y ;

Zhou, L ;

Huang, Y ;

Zhang, JW ;

Xiong, SM ;

Chen, SJ ;

Wang, ZY ;

Chen, Z ;

Chen, GQ .

LEUKEMIA, 2000, 14 (02) :262-270

[13]

Carlisle DL, 2000, MOL CARCINOGEN, V28, P111, DOI 10.1002/1098-2744(200006)28:2<111::AID-MC7>3.0.CO

[14]

2-Y

[15] Apoptosis and p53 induction in human lung fibroblasts exposed to chromium (VI): Effect of ascorbate and tocopherol [J].

Carlisle, DL ;

Pritchard, DE ;

Singh, J ;

Owens, BM ;

Blankenship, LJ ;

Orenstein, JM ;

Patierno, SR .

TOXICOLOGICAL SCIENCES, 2000, 55 (01) :60-68

[16] Opposite effect of NF-κB and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite [J].

Chen, F ;

Lu, YJ ;

Zhang, Z ;

Vallyathan, V ;

Ding, M ;

Castranova, V ;

Shi, XL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (14) :11414-11419

[17]

Chen GQ, 1996, BLOOD, V88, P1052

[18]

Chen Nan-Yue, 2000, Journal of Environmental Pathology Toxicology and Oncology, V19, P287

[19]

Chen RF, 2000, RARE METALS, V19, P231

[20]

Chen YC, 1998, J CELL PHYSIOL, V177, P324, DOI 10.1002/(SICI)1097-4652(199811)177:2<324::AID-JCP14>3.0.CO

← 1 2 3 4 5 6 →