Drosophila telomeres:: the non-telomerase alternative

被引：23

作者：

Melnikova, L ^{[1
]}

Georgiev, P ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Gene Biol, Moscow 119334, Russia

来源：

CHROMOSOME RESEARCH | 2005年 / 13卷 / 05期

基金：

俄罗斯基础研究基金会;

关键词：

Drosophila; retrotransposons; TAS; telomere; t-loop;

D O I：

10.1007/s10577-005-0992-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In most eukaryotes, telomeres are composed of simple repetitive sequences renewable by telomerase. By contrast, Drosophila telomeres comprise arrays of non-LTR retrotransposons HeT-A, TART, and TAHRE belonging to three different families. However, closer inspection reveals that the two quite different telomere systems share quite a few components and regulatory circuits. Here we present the current knowledge on Drosophila telomeres and discuss the possible mechanisms of telomere length control.

引用

页码：431 / 441

页数：11

共 71 条

[1] TAHRE, a novel telomeric Retrotransposon from Drosophila melanogaster, reveals the origin of Drosophila telomeres [J].

Abad, JP ;

de Pablos, B ;

Osoegawa, K ;

de Jong, PJ ;

Martín-Gallardo, A ;

Villasante, A .

MOLECULAR BIOLOGY AND EVOLUTION, 2004, 21 (09) :1620-1624

[2] Genomic analysis of Drosophila melanogaster telomeres:: Full-length copies of HeT-A and TART elements at telomeres [J].

Abad, JP ;

de Pablos, B ;

Osoegawa, K ;

de Jong, PJ ;

Martín-Gallardo, A ;

Villasante, A .

MOLECULAR BIOLOGY AND EVOLUTION, 2004, 21 (09) :1613-1619

[3] Rap1p telomere association is not required for mitotic stability of a C3TA2 telomere in yeast [J].

Alexander, MK ;

Zakian, VA .

EMBO JOURNAL, 2003, 22 (07) :1688-1696

[4]

Belenkaya T, 1998, GENETICS, V150, P687

[5] Which end: dissecting Ku's function at telomeres and double-strand breaks [J].

Bertuch, AA ;

Lundblad, V .

GENES & DEVELOPMENT, 2003, 17 (19) :2347-2350

[6] Telomere protection without a telornerase:: The role of ATM and Mre11 in Drosophila telomere maintenance [J].

Bi, XL ;

Wei, SCD ;

Rong, YKS .

CURRENT BIOLOGY, 2004, 14 (15) :1348-1353

[7] PROGRESSIVE LOSS OF DNA-SEQUENCES FROM TERMINAL CHROMOSOME DEFICIENCES IN DROSOPHILA-MELANOGASTER [J].

BIESSMANN, H ;

MASON, JM .

EMBO JOURNAL, 1988, 7 (04) :1081-1086

[8] FREQUENT TRANSPOSITIONS OF DROSOPHILA-MELANOGASTER HET-A TRANSPOSABLE ELEMENTS TO RECEDING CHROMOSOME ENDS [J].

BIESSMANN, H ;

CHAMPION, LE ;

OHAIR, M ;

IKENAGA, K ;

KASRAVI, B ;

MASON, JM .

EMBO JOURNAL, 1992, 11 (12) :4459-4469

[9] Telomerase-independent mechanisms of telomere elongation [J].

Biessmann, H ;

Mason, JM .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2003, 60 (11) :2325-2333

[10] ADDITION OF TELOMERE-ASSOCIATED HET DNA-SEQUENCES HEALS BROKEN CHROMOSOME ENDS IN DROSOPHILA [J].

BIESSMANN, H ;

MASON, JM ;

FERRY, K ;

DHULST, M ;

VALGEIRSDOTTIR, K ;

TRAVERSE, KL ;

PARDUE, ML .

CELL, 1990, 61 (04) :663-673

← 1 2 3 4 5 6 7 8 →