Drosophila telomeres:: the non-telomerase alternative

被引：23

作者：

Melnikova, L ^{[1
]}

Georgiev, P ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Gene Biol, Moscow 119334, Russia

来源：

CHROMOSOME RESEARCH | 2005年 / 13卷 / 05期

基金：

俄罗斯基础研究基金会;

关键词：

Drosophila; retrotransposons; TAS; telomere; t-loop;

D O I：

10.1007/s10577-005-0992-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In most eukaryotes, telomeres are composed of simple repetitive sequences renewable by telomerase. By contrast, Drosophila telomeres comprise arrays of non-LTR retrotransposons HeT-A, TART, and TAHRE belonging to three different families. However, closer inspection reveals that the two quite different telomere systems share quite a few components and regulatory circuits. Here we present the current knowledge on Drosophila telomeres and discuss the possible mechanisms of telomere length control.

引用

页码：431 / 441

页数：11

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